Gangliocytic Paraganglioma with Carcinoma of the Ampulla of Vater

The patient was a "73" -year-old woman who visited our hospital with the chief complaint of weight loss. Upper gastrointestinal endoscopy revealed an enlarged ampulla of Vater, and a biopsy led to a diagnosis of Group "4" gastric carcinoma; suspicious of adenocarcinoma. There wer...

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Bibliographic Details
Published in:Internal Medicine 2018/09/15, Vol.57(18), pp.2663-2668
Main Authors: Sekine, Masanari, Miyatani, Hiroyuki, Matsumoto, Keita, Kashima, Hitomi, Koito, Yudai, Miura, Takaya, Takahashi, Yuko, Tsuboi, Rumiko, Ishii, Takehiro, Fujiwara, Junichi, Uehara, Takeshi, Urayoshi, Shunsuke, Yuhashi, Kazuhito, Asano, Takeharu, Sagihara, Noriyoshi, Matsumoto, Satohiro, Mashima, Hirosato
Format: Article
Language:English
Subjects:
Adenocarcinoma
Ampulla of Vater
Biopsy
carcinoma
Case Report
Duodenum
endoscopic papillectomy
Endoscopy
gangliocytic paraganglioma
Gastric cancer
Internal medicine
Lesions
Muscles
Paraganglioma
Sphincter
Therapeutic applications
Weight loss
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Summary:The patient was a "73" -year-old woman who visited our hospital with the chief complaint of weight loss. Upper gastrointestinal endoscopy revealed an enlarged ampulla of Vater, and a biopsy led to a diagnosis of Group "4" gastric carcinoma; suspicious of adenocarcinoma. There were no findings suggesting invasion into the muscle layer of duodenum, despite tumor mass formation being observed in the sphincter of Oddi. We performed endoscopic papillectomy for both diagnostic and therapeutic purposes. Pathologically, a well-differentiated adenocarcinoma existed in the superficial layer of the mucous membrane of the papilla of Vater, and gangliocytic paraganglioma was present in the deep portion. The resected margins of both lesions were negative.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.0464-17