Changes of Arterial Pulse Waveform Characteristics with Gestational Age during Normal Pregnancy

Arterial pulse waveform analysis has been widely used to reflect physiological changes in the cardiovascular system. This study aimed to comprehensively investigate the changes of waveform characteristics of both photoplethysmographic (PPG) and radial pulses with gestational age during normal pregna...

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Bibliographic Details
Published in:Scientific reports 2018-10, Vol.8 (1), p.15571-8, Article 15571
Main Authors: Li, Kunyan, Zhang, Song, Yang, Lin, Jiang, Hongqing, Chi, Zhenyu, Wang, Anran, Yang, Yimin, Li, Xuwen, Hao, Dongmei, Zhang, Lei, Zheng, Dingchang
Format: Article
Language:English
Subjects:
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Age
Cardiovascular system
Gestational age
Heart rate
Humanities and Social Sciences
multidisciplinary
Pregnancy
Prenatal development
Science
Science (multidisciplinary)
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Summary:Arterial pulse waveform analysis has been widely used to reflect physiological changes in the cardiovascular system. This study aimed to comprehensively investigate the changes of waveform characteristics of both photoplethysmographic (PPG) and radial pulses with gestational age during normal pregnancy. PPG and radial pulses were simultaneously recorded from 130 healthy pregnant women at seven gestational time points. After normalizing the arterial pulse waveforms, the abscissa of notch point, the total pulse area and the reflection index were extracted and compared between different measurement points and between the PPG and radial pulses using post-hoc multiple comparisons with Bonferrioni correction. The results showed that the effect of gestational age on all the three waveform characteristics was significant (all p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-33890-1