Grimon: graphical interface to visualize multi-omics networks

Abstract Summary Rapid advances in high-throughput sequencing technologies have enabled more efficient acquisition of massive amount of multi-omics data. However, interpretation of the underlying relationships across multi-omics networks has not been fully succeeded, partly due to the lack of effect...

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Bibliographic Details
Published in:Bioinformatics 2018-11, Vol.34 (22), p.3934-3936
Main Authors: Kanai, Masahiro, Maeda, Yuichi, Okada, Yukinori
Format: Article
Language:English
Subjects:
Applications Notes
data analysis
data collection
high-throughput nucleotide sequencing
multiomics
technology
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Summary:Abstract Summary Rapid advances in high-throughput sequencing technologies have enabled more efficient acquisition of massive amount of multi-omics data. However, interpretation of the underlying relationships across multi-omics networks has not been fully succeeded, partly due to the lack of effective methods in visualization. To aid interpretation of the results from such multi-omics data, we here present Grimon (Graphical interface to visualize multi-omics networks), an R package that visualizes high-dimensional multi-layered data sets in three-dimensional parallel coordinates. Grimon enables users to intuitively and interactively explore their analyzed data, helping their understanding of multiple inter-layer connections embedded in high-dimensional complex data. Availability and implementation Grimon is freely available at https://github.com/mkanai/grimon as an R package with example omics data sets. Supplementary information Supplementary data are available at bioinformatics online.
ISSN:1367-4803
1460-2059
1460-2059
1367-4811
DOI:10.1093/bioinformatics/bty488