Diagnostic Approach to Fine Needle Aspirations of Cystic Lesions of the Salivary Gland

Fine needle aspiration (FNA) has diagnostic and therapeutic value in the management of salivary gland cysts. Rendering an accurate diagnosis from an aspirated salivary gland cyst is challenging because of the broad differential diagnosis, possibility of sampling error, frequent hypocellularity of sp...

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Bibliographic Details
Published in:Head & neck pathology (Totowa, N.J.) N.J.), 2018-12, Vol.12 (4), p.548-561
Main Authors: Pantanowitz, Liron, Thompson, Lester D. R., Rossi, Esther Diana
Format: Article
Language:English
Subjects:
Biopsy, Fine-Needle
Cysts - diagnosis
Cysts - pathology
Dentistry
Humans
Invited Review
Medicine
Medicine & Public Health
Oral and Maxillofacial Surgery
Otorhinolaryngology
Pathology
Salivary Gland Diseases - diagnosis
Salivary Gland Diseases - pathology
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Summary:Fine needle aspiration (FNA) has diagnostic and therapeutic value in the management of salivary gland cysts. Rendering an accurate diagnosis from an aspirated salivary gland cyst is challenging because of the broad differential diagnosis, possibility of sampling error, frequent hypocellularity of specimens, morphologic heterogeneity, and overlapping cytomorphology of many cystic entities. To date, there have been no comprehensive review articles providing a practical diagnostic approach to FNA of cystic lesions of salivary glands. This article reviews the cytopathology of salivary gland cysts employing 2017 World Health Organization terminology, addresses the accuracy of FNA, and presents The Milan System approach for reporting in cystic salivary gland cases. The utility of separating FNA specimens from salivary gland cysts, based upon the presence of mucin and admixed lymphocytes in cyst fluid is demonstrated. A reliable approach to interpreting FNA specimens from patients with cystic salivary gland lesions is essential to accurately determine which of these patients may require subsequent surgery.
ISSN:1936-055X
1936-0568
DOI:10.1007/s12105-018-0904-8