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Antimicrobial Susceptibility of Pseudomonas aeruginosa to Ceftazidime-Avibactam, Ceftolozane-Tazobactam, Piperacillin-Tazobactam, and Meropenem Stratified by U.S. Census Divisions: Results from the 2017 INFORM Program
isolates ( = 1,909) were collected from 70 U.S. medical centers, and their susceptibilities were tested using the broth microdilution method. Ceftazidime-avibactam (MIC /MIC , 2/8 mg/liter) and ceftolozane-tazobactam (MIC /MIC , 0.5/2 mg/liter) were the most active (i.e., had the highest susceptibil...
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Published in: | Antimicrobial agents and chemotherapy 2018-12, Vol.62 (12) |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | isolates (
= 1,909) were collected from 70 U.S. medical centers, and their susceptibilities were tested using the broth microdilution method. Ceftazidime-avibactam (MIC
/MIC
, 2/8 mg/liter) and ceftolozane-tazobactam (MIC
/MIC
, 0.5/2 mg/liter) were the most active (i.e., had the highest susceptibility rates) compounds after colistin, with national susceptibility rates of 96.9% and 97.5%, respectively. Overall, piperacillin-tazobactam (MIC
/MIC
, 4/128 mg/liter) and meropenem (MIC
/MIC
, 0.5/16 mg/liter) were active against 77.5% and 76.0% of the isolates, respectively. Susceptibility variations across census divisions were documented for many antimicrobials. |
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ISSN: | 0066-4804 1098-6596 |
DOI: | 10.1128/AAC.01587-18 |