Microsurgical clipping and endovascular flow diversion of ruptured anterior circulation blood blister-like aneurysms

• Published in: Interventional neuroradiology 2018-12, Vol.24 (6), p.615-623
• Main Authors: Hellstern, V, Aguilar-Pérez, M, AlMatter, M, Bhogal, P, Henkes, E, Ganslandt, O, Henkes, H
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aneurysm; Aneurysm, Ruptured - diagnostic imaging; Aneurysm, Ruptured - surgery; Angiography, Digital Subtraction; Blister - diagnostic imaging; Blister - surgery; Blood Vessel Prosthesis; Cerebral Revascularization - adverse effects; Cerebral Revascularization - methods; Endovascular Procedures - adverse effects; Endovascular Procedures - methods; Female; Follow-Up Studies; Headache - etiology; Humans; Male; Middle Aged; Patient Safety; Recurrence; Retrospective Studies; Subarachnoid Hemorrhage - diagnostic imaging; Subarachnoid Hemorrhage - surgery; Tomography, X-Ray Computed; Treatment Outcome; Young Adult
• ISSN: 1591-0199; 2385-2011
• DOI: 10.1177/1591019918785911

Background Detection and treatment of blister-like intracranial aneurysms as a source of subarachnoid hemorrhage (SAH) can be challenging. In the past the results of both microsurgical and endovascular treatment were difficult. We present our experience with the treatment of blister-like aneurysms in the acute phase of SAH using microsurgical clipping, endovascular parent vessel occlusion or flow diversion. Methods A retrospective analysis of the cases of eight consecutive patients presenting in the acute phase after SAH from an intracranial blister aneurysm was performed. The demographic data of the patients, aneurysm characteristics, the clinical results of the treatment and the follow-up examinations were recorded. Procedural safety margins and aneurysm occlusion on follow-up digital subtraction angiography were the main interest of this evaluation. Results Between January 2012 and November 2017 a total of eight ruptured blister aneurysms were treated in our center, six patients endovascularly. Five patients were treated in the acute phase of SAH, four by flow diversion. All endovascular procedures were feasible and no procedure-related complications were observed, especially no recurrent hemorrhage. In the first angiographic follow-up all blood blister-like aneurysms were completely occluded; two of the six patients treated by flow diverter implantation showed mild, transient intimal hyperplasia without clinical symptoms or the need for treatment. Conclusions Endovascular flow diversion is a viable option in the acute phase after SAH due to the rupture of a blister aneurysm. Implants with reduced thrombogenicity, obviating dual-platelet function inhibition, and flow diverters for vessel bifurcations would extend the indications for this treatment modality.