Sulfasalazine-Induced Interstitial Fibrosis

Sulfasalazine has been used in the treatment of inflammatory bowel disease for over 60 years. Although the drug is frequently associated with gastrointestinal adverse effects, pulmonary adverse effects are very rare. Herein, we report a case of interstitial fibrosis resulting from 4-month sulfasalaz...

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Bibliographic Details
Published in:The Eurasian journal of medicine 2018-10, Vol.50 (3), p.207-209
Main Authors: Kerget, Bugra, Araz, Omer, Ucar, Elif Yilmazel, Aydin, Ozkan, Akgun, Metin, Saglam, Leyla
Format: Article
Language:English
Subjects:
Anemia
Antibiotics
Arthralgia
Case Report
Case reports
Case studies
Chronic obstructive lung disease
Colitis
Complications and side effects
Dosage and administration
Drug therapy
Fibrosis
Gastrointestinal diseases
Headache
Hemolytic anemia
Hepatitis
Lung diseases
Medical schools
Nonsteroidal anti-inflammatory agents
Pulmonary fibrosis
Rash
Respiratory tract diseases
Risk factors
Sulfasalazine
Toxicity
Ulcerative colitis
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Description
Summary:Sulfasalazine has been used in the treatment of inflammatory bowel disease for over 60 years. Although the drug is frequently associated with gastrointestinal adverse effects, pulmonary adverse effects are very rare. Herein, we report a case of interstitial fibrosis resulting from 4-month sulfasalazine therapy for ulcerative colitis in a patient under long-term follow-up in our clinic due to chronic obstructive pulmonary disease.
ISSN:1308-8734
1308-8742
DOI:10.5152/eurasianjmed.2018.17302