Instantaneous restoration of cardiac output by noninvasive positive pressure ventilation in a patient with obesity hypoventilation syndrome

Summary We report a 30-year-old man with severe obesity hypoventilation syndrome (OHVS) complicated by right-sided heart failure. Polysomnography revealed severe obstructive sleep apnea with apnea–hypopnea index (AHI) 70.4/h and gradual decrease in minimum oxygen saturation (SpO2 ) from 86% before s...

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Bibliographic Details
Published in:Journal of cardiology cases 2011-02, Vol.3 (1), p.e40-e42
Main Authors: Yoshida, Masayoshi, MD, Ando, Shin-ichi, MD, PhD, Kadokami, Toshiaki, MD, PhD, Narita, Sumito, MD, Momii, Hidetoshi, MD, PhD, Sato, Yumi, MT, Kiyokawa, Tomoko, MT, Nakao, Chikako, MT
Format: Article
Language:English
Subjects:
Cardiovascular
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Summary:Summary We report a 30-year-old man with severe obesity hypoventilation syndrome (OHVS) complicated by right-sided heart failure. Polysomnography revealed severe obstructive sleep apnea with apnea–hypopnea index (AHI) 70.4/h and gradual decrease in minimum oxygen saturation (SpO2 ) from 86% before sleep to 36% during sleep. Cardiac output (CO) was suppressed from 3.9 L/min before sleep to 2.5 L/min during sleep. Noninvasive positive pressure ventilation (NPPV) treatment drastically restored CO to the level before sleep, and improved AHI to 9.4/h and minimum SpO2 to 87%. NPPV may provide rapid and powerful symptom relief in patients with OHVS complicated with right sided heart failure.
ISSN:1878-5409
1878-5409
DOI:10.1016/j.jccase.2010.10.001