Phenolic antioxidants isolated from the flowers of Osmanthus fragrans

O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl3 sub-extract of O. fragrans. The structures were elucidated by interpreting thei...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2012-09, Vol.17 (9), p.10724-10737
Main Authors: Hung, Chien-Ya Hung, Tsai, Yu-Cheng, Li, Kuo-Yu
Format: Article
Language:English
Subjects:
Antioxidants
Antioxidants - chemistry
Antioxidants - isolation & purification
Antioxidants - pharmacology
Biphenyl Compounds - metabolism
Flowers - chemistry
Free Radical Scavengers - chemistry
Free Radical Scavengers - isolation & purification
Free Radical Scavengers - pharmacology
Hydrogen Peroxide - metabolism
Oleaceae - chemistry
Phenols - chemistry
Phenols - isolation & purification
Phenols - pharmacology
Picrates - metabolism
Polyphenols
Tea
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Summary:O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl3 sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC50 values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H2O2 scavenging ability, with IC50 values of 10.5, 23.4, and 13.4 μM, respectively.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules170910724