Multiple Sclerosis Functional Composite (MSFC): Scoring Instructions

It is important to assess the clinical outcome in patients with multiple sclerosis (MS) both during individual clinical follow-up and in clinical trials. The National MS Society's Clinical Outcomes Assessment Task Force has developed and recommended a multidimensional clinical outcome measure,...

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Bibliographic Details
Published in:Noro-Psikiyatri Arsivi 2018-01, Vol.55 (Suppl 1), p.S46-S48
Main Author: Tiftikçioğlu, Bedile İrem
Format: Article
Language:English
Subjects:
Review
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Summary:It is important to assess the clinical outcome in patients with multiple sclerosis (MS) both during individual clinical follow-up and in clinical trials. The National MS Society's Clinical Outcomes Assessment Task Force has developed and recommended a multidimensional clinical outcome measure, namely Multiple Sclerosis Functional Composite (MSFC). This enables to measure the impact of MS in three key clinical dimensions: leg function and ambulation, arm and hand function, and cognitive function. Raw scores in different measurement scales are transformed into standard comparable scores (z-scores) and an overall composite score is calculated. In this review, the rationale behind the MSFC, administration and calculation of the composite score is discussed in detail.
ISSN:1300-0667
1309-4866
DOI:10.29399/NPA.23330