Adverse effect of prematurely elevated progesterone in in vitro fertilization cycles: a literature review

Premature progesterone (P) elevation was commonly seen in IVF prior to the utilization of GnRH analogues for suppression of endogenous gonadotropin release. The cause and effect of premature P elevation has finally been better elucidated in the past decade. Although still occurring in 5–38% of all I...

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Bibliographic Details
Published in:Biology of reproduction 2018-07, Vol.99 (1), p.45-51
Main Authors: Evans, Michael B, Healy, Mae W, DeCherney, Alan H, Hill, Micah J
Format: Article
Language:English
Subjects:
Embryo Transfer
Endometrium
Female
Fertilization in Vitro
Humans
implantation
implantationwindow
In vitro fertilization
IVF
Ovulation Induction
Pregnancy
Pregnancy Outcome
prematurely elevated progesterone
progesterone
Progesterone - adverse effects
Progesterone - blood
Reproductive health
Review
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Summary:Premature progesterone (P) elevation was commonly seen in IVF prior to the utilization of GnRH analogues for suppression of endogenous gonadotropin release. The cause and effect of premature P elevation has finally been better elucidated in the past decade. Although still occurring in 5–38% of all IVF cycles, the adverse effects of premature P elevation on pregnancy outcomes are now well known.
ISSN:0006-3363
1529-7268
DOI:10.1093/biolre/ioy082