Plasma Cell-Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients

Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related morbidity and mortality. A novel plasma cell-free DNA next-generation sequencing test detected an uncommon presentation of and recurrent and meta...

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Bibliographic Details
Published in:Open forum infectious diseases 2018-12, Vol.5 (12), p.ofy301-ofy301
Main Authors: Fung, Monica, Zompi, Simona, Seng, Hon, Hollemon, Desiree, Parham, Adama, Hong, David K, Bercovici, Sivan, Dolan, Estelle, Lien, Kathy, Teraoka, Justin, Logan, Aaron C, Chin-Hong, Peter
Format: Article
Language:English
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Brief Report
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Summary:Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related morbidity and mortality. A novel plasma cell-free DNA next-generation sequencing test detected an uncommon presentation of and recurrent and metastatic complications of bacteremia before standard microbiology.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofy301