CHA2DS2-VASc score predicts exercise intolerance in young and middle-aged male patients with asymptomatic atrial fibrillation

Exercise intolerance among the clinical symptoms in patients with atrial fibrillation (AF) has usually been masked by their adjusted life style. We sought to assess the role of CHA 2 DS 2 -VASc score to predict exercise intolerance in asymptomatic AF patients, and further examine whether the relatio...

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Bibliographic Details
Published in:Scientific reports 2018-12, Vol.8 (1), p.1-8, Article 18039
Main Authors: Yi, Jeong-Eun, Lee, Young Soo, Choi, Eue-Keun, Cha, Myung-Jin, Kim, Tae-Hoon, Park, Jin-Kyu, Lee, Jung-Myung, Kang, Ki-Woon, Shim, Jaemin, Uhm, Jae-Sun, Kim, Jun, Kim, Changsoo, Kim, Jin-Bae, Park, Hyung Wook, Joung, Boyoung, Park, Junbeom
Format: Article
Language:English
Subjects:
692/4019/592/75/230
692/699/75/29/1309
Cardiac arrhythmia
Electrocardiography
Fibrillation
Humanities and Social Sciences
Intolerance
Middle age
multidisciplinary
Multivariate analysis
Risk assessment
Science
Science (multidisciplinary)
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Summary:Exercise intolerance among the clinical symptoms in patients with atrial fibrillation (AF) has usually been masked by their adjusted life style. We sought to assess the role of CHA 2 DS 2 -VASc score to predict exercise intolerance in asymptomatic AF patients, and further examine whether the relationship differs by age and gender. Among the 6,275 participants of the prospective Korean registry of the Comparison study of Drugs for symptom control and complication prevention of Atrial Fibrillation (CODE-AF), 1,080 AF patients who underwent exercise treadmill testing were studied. Exercise intolerance was defined as a peak exercise capacity of 7 metabolic equivalents (METs) or less, and the patients were divided into two groups for the analysis: ≤7 METs (n = 131) and >7 METs (n = 949). Patients with exercise intolerance had a significantly higher CHA 2 DS 2 -VASc score than those without (3.1 ± 1.3 vs. 2.0 ± 1.5, p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-36185-7