Hypoglycemia Unawareness in Insulinoma Revealed with Flash Glucose Monitoring Systems

The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which faci...

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Bibliographic Details
Published in:Internal Medicine 2018/12/01, Vol.57(23), pp.3407-3412
Main Authors: Sugawa, Taku, Murakami, Takaaki, Yabe, Daisuke, Kashima, Riko, Tatsumi, Makiko, Ooshima, Shinobu, Joo, Erina, Wada, Keiko, Yoshizawa, Atsushi, Masui, Toshihiko, Nakamoto, Yuji, Yamauchi, Yuki, Kodama, Yuzo, Iemura, Yoshiki, Ogura, Masahito, Yasoda, Akihiro, Inagaki, Nobuya
Format: Article
Language:English
Subjects:
Awareness
Blood
Blood Glucose - analysis
Blood Glucose Self-Monitoring - methods
Case Report
continuous glucose monitoring
Delayed Diagnosis
Diagnosis
DOTATOC
Exercise
Female
flash glucose monitoring
Glucose
Glucose monitoring
Humans
Hypoglycemia
Hypoglycemia - diagnosis
Hypoglycemia - etiology
hypoglycemia unawareness
Insulinoma
Insulinoma - complications
Insulinoma - diagnosis
Internal medicine
Middle Aged
Pancreatic Neoplasms - complications
Pancreatic Neoplasms - diagnosis
Postprandial Period
Unconsciousness - etiology
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Summary:The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.1173-18