Vanishing cerebral vasculitis in a patient with Lewy pathology

Immune-mediated mechanisms are involved in the pathogenesis of both cerebral vasculitis and Parkinson’s disease（PD, brainstem-predominant Lewy pathology）, but the presentation of cerebral vasculitis with comorbid Lewy pathology has not yet been reported. Here we present a case of pathologically conf...

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Bibliographic Details
Published in:Journal of biomedical research 2017-01, Vol.31 (6), p.559-562
Main Authors: Liapounova, Natalia, Azar, Kamran H, Findlay, J Max, Lu, Jian-Qiang
Format: Article
Language:English
Subjects:
Case Report
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Summary:Immune-mediated mechanisms are involved in the pathogenesis of both cerebral vasculitis and Parkinson’s disease（PD, brainstem-predominant Lewy pathology）, but the presentation of cerebral vasculitis with comorbid Lewy pathology has not yet been reported. Here we present a case of pathologically confirmed vasculitis in a 73-year-old male patient whose postmortem examination revealed Lewy pathology diagnostic of PD. This case study suggests a comorbidity of cerebral vasculitis and Lewy pathology, as well as potential pathogenic interactions between these two disorders with immune-mediated mechanisms.
ISSN:1674-8301
2352-4685
DOI:10.7555/JBR.31.20160119