Utility and Limitation of Preoperative Neutrophil Lymphocyte Ratio as a Prognostic Factor in Hepatocellular Carcinoma

[ABSTRACT] [Background] The neutrophil lymphocyte ratio (NLR) has been proposed to be a surrogate marker of inflammation and immunological status and to have prognostic value in various malignancies. This study was conducted to clarify the prognostic significance of preoperative NLR in hepatocellula...

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Bibliographic Details
Published in:YONAGO ACTA MEDICA 2018, Vol.61 (4), p.197-203
Main Authors: Uchinaka, Ei, Amisaki, Masataka, Morimoto, Masaki, Tokuyasu, Naruo, Sakamoto, Teruhisa, Honjo, Soichiro, Saito, Hiroaki, Fujiwara, Yoshiyuki
Format: Article
Language:English
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Summary:[ABSTRACT] [Background] The neutrophil lymphocyte ratio (NLR) has been proposed to be a surrogate marker of inflammation and immunological status and to have prognostic value in various malignancies. This study was conducted to clarify the prognostic significance of preoperative NLR in hepatocellular carcinoma (HCC). [Methods] We enrolled 135 patients with histologicallyproven HCC who underwent initial curative hepatectomy. Based on the median NLR values, patients were divided into: NLR>-2.0 (NLR-high, n=69) and NLR
ISSN:0513-5710
1346-8049
DOI:10.33160/yam.2018.12.002