Rare Isolated Renal Involvement with Marginal Zone B Cell Lymphoma: A Case Report with Literature Review of Contemporary Management Strategies

Marginal zone B cell lymphomas are divided into nodal, extranodal and splenic types. Renal involvement by extranodal B cell lymphoma is extremely rare with an incidence of about 0.1%. We present a case of a 79-year-old Caucasian male with progressive renal failure and isolated left renal extranodal...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2018-11, Vol.10 (11), p.e3560
Main Authors: Khalil, Muhammad J, Malik, Mustafa N, Ahmed, Maryam, Rafae, Abdul, Anwer, Faiz
Format: Article
Language:English
Subjects:
Biopsy
Blood
Case reports
Chemotherapy
Clinical trials
Hemoglobin
Immunoglobulins
Infections
Inflammation
Kinases
Lymphatic system
Lymphocytes
Lymphoma
Medical prognosis
Microscopy
Oncology
Patients
Proteins
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Summary:Marginal zone B cell lymphomas are divided into nodal, extranodal and splenic types. Renal involvement by extranodal B cell lymphoma is extremely rare with an incidence of about 0.1%. We present a case of a 79-year-old Caucasian male with progressive renal failure and isolated left renal extranodal marginal zone lymphoma. Asymptomatic immunoglobulin (Ig) M monoclonal gammopathy along with bone marrow involvement by lymphoma was observed. Contemporary management options including radiotherapy (RT), chemotherapy, immune-modulating agents and novel chemotherapy-free regimens.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.3560