Web-Based Tailored Intervention to Support Optimal Medication Adherence Among Kidney Transplant Recipients: Pilot Parallel-Group Randomized Controlled Trial

Optimal immunosuppressive medication adherence is essential to graft survival. Transplant-TAVIE is a Web-based tailored intervention developed to promote this adherence. The objective of our study was to evaluate the Transplant-TAVIE intervention's acceptability, feasibility, and preliminary ef...

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Bibliographic Details
Published in:JMIR formative research 2018-07, Vol.2 (2), p.e14
Main Authors: Côté, José, Fortin, Marie-Chantal, Auger, Patricia, Rouleau, Geneviève, Dubois, Sylvie, Boudreau, Nathalie, Vaillant, Isabelle, Gélinas-Lemay, Élisabeth
Format: Article
Language:English
Subjects:
Clinical trials
Immunosuppressive agents
Intervention
Kidney transplants
Nursing
Original Paper
Patient compliance
Problem solving
Questionnaires
Websites
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Summary:Optimal immunosuppressive medication adherence is essential to graft survival. Transplant-TAVIE is a Web-based tailored intervention developed to promote this adherence. The objective of our study was to evaluate the Transplant-TAVIE intervention's acceptability, feasibility, and preliminary efficacy. In a pilot, parallel-group, randomized controlled trial, we randomly assigned a convenience sample of 70 kidney transplant patients on immunosuppressive medication either to an experimental group (Transplant-TAVIE) or to a control group (existing websites). Kidney transplant recipients had to be older than 18 years, be taking immunosuppressant medication, and have access to the internet to participate in this study. Transplant-TAVIE was composed of three interactive Web-based sessions hosted by a virtual nurse. We documented user appreciation of and exposure to the intervention. Furthermore, we assessed medication adherence, medication self-efficacy, intake-related skills, and medication side effects at baseline and 3 and 6 months later. Analyses of variance were used to assess intergroup differences over time. After baseline questionnaire completion, participants were randomly assigned either to Transplant-TAVIE (n=35) or to the websites (n=35) group. All participants had received their kidney graft
ISSN:2561-326X
2561-326X
DOI:10.2196/formative.9707