A Review of Antiplatelet Activity of Traditional Medicinal Herbs on Integrative Medicine Studies

Thrombotic events mainly occurred by platelet activation and aggregation. The vascular occlusion causes serious disease states such as unstable angina, ischemic stroke, and heart attack. Due to the pervading of thrombotic diseases, new antiplatelet drugs are necessary for preventing and treating art...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2019-01, Vol.2019 (2019), p.1-18
Main Authors: Kim, Kyungho, Park, Kwang-Il
Format: Article
Language:English
Subjects:
Adenosine diphosphate
Angina
Angina pectoris
Antiplatelet therapy
Aspirin
Blood clots
Blood platelets
Cardiology
Cardiovascular disease
Chemical compounds
Chromatography
Disease prevention
Drug dosages
Drug therapy
Enzymes
Evidence-based medicine
FDA approval
Herbal medicine
Herbs
Integrative medicine
Ischemia
Kinases
Medicinal herbs
Medicinal plants
Metabolites
Mode of action
Myocardial infarction
Occlusion
Pharmaceuticals
Platelets
Review
Side effects
Stroke
Thromboembolism
Thrombosis
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Summary:Thrombotic events mainly occurred by platelet activation and aggregation. The vascular occlusion causes serious disease states such as unstable angina, ischemic stroke, and heart attack. Due to the pervading of thrombotic diseases, new antiplatelet drugs are necessary for preventing and treating arterial thrombosis without adverse side effects. Traditional medicinal herbs have been used for the treatment of human ailments for a long time. The clinically useful and safe products from traditional medicinal herbs were identified and developed in numerous pharmacological approaches. A complementary system of traditional medicinal herbs is a good candidate for pharmacotherapy. However, it still has a limitation in its function and efficacy. Thus, it is necessary to study the mode of action of traditional medicinal herbs as alternative therapeutic agents. In this review, we focused on our current understanding of the regulatory mechanisms of traditional medicinal herbs in antiplatelet activity and antithrombotic effect of traditional medicinal herbs on platelet function.
ISSN:1741-427X
1741-4288
DOI:10.1155/2019/7125162