Spontaneous testicular tumor regression: case report and historical review

Spontaneous regression of a primary testicular germ-cell tumour (GCT), over time known as 'Burned out', 'Shrinking Seminoma', 'pT0', 'Burnout' or 'Spontaneous Regression', is an uncommon, generally metastatic phenomenon, which may present elevated tu...

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Bibliographic Details
Published in:Ecancermedicalscience 2018-12, Vol.12, p.888-888
Main Authors: Astigueta, Juan C, Abad-Licham, Milagros A, Agreda, Folker M, Leiva, Benjamin A, De la Cruz, Jorge L
Format: Article
Language:English
Subjects:
Abdomen
Biomarkers
Case reports
Chemotherapy
Disease
Family medical history
Histology
Lymphatic system
Lymphoma
Medical imaging
Medical prognosis
Metastasis
Patients
Review
Testicular cancer
Tumors
Ultrasonic imaging
Urology
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Summary:Spontaneous regression of a primary testicular germ-cell tumour (GCT), over time known as 'Burned out', 'Shrinking Seminoma', 'pT0', 'Burnout' or 'Spontaneous Regression', is an uncommon, generally metastatic phenomenon, which may present elevated tumour markers and a suspicious testicular ultrasound image. The histological study of the testicle demonstrated morphological changes of complete or partial tumour regression and found fibrous scarring and other characteristic changes of this phenomenon, which in some cases include vestiges of GCT. There are few publications on testicular GCT tumour regression and those that exist present limited data on the biology of the disease and its etiopathogenesis. This entity was recently recognised in the latest edition of the World Health Organization's (WHO) Classification of Tumours. We present our clinical, imaging, laboratory, cytohistological and management experience, as well as a historical review of the literature.
ISSN:1754-6605
1754-6605
DOI:10.3332/ecancer.2018.888