Lung stereotactic body radiotherapy after past ablative therapy: a single institution case series

Non-small-cell lung cancer recurs locally 10-40% of the time after local therapy, presenting a therapeutic challenge given poor pulmonary reserve. Herein, we seek to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) for retreatment of such patients. We identified and reviewed...

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Bibliographic Details
Published in:Lung cancer management 2018-12, Vol.7 (3)
Main Authors: Wegner, Rodney E, Ahmed, Nissar, Hasan, Shaakir, Schumacher, Lana Y, Colonias, Athanasios
Format: Article
Language:English
Subjects:
brachytherapy
Cancer therapies
Case Series
Failure
Lung cancer
Patients
Planning
Radiation therapy
radiofrequency ablation
SBRT
Tumors
vicryl mesh
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Summary:Non-small-cell lung cancer recurs locally 10-40% of the time after local therapy, presenting a therapeutic challenge given poor pulmonary reserve. Herein, we seek to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) for retreatment of such patients. We identified and reviewed clinical outcomes in ten patients with recurrent non-small-cell lung cancer after past vicryl mesh brachytherapy. Ten patients with a median age of 77 were treated to a median dose of 48 Gy in five fractions. Local control at 1 year was 88%. There was one distant failure at 29 months. There was no significant toxicity after SBRT. SBRT is safe and effective when used for re-irradiation after past ablative therapies.
ISSN:1758-1966
1758-1974
DOI:10.2217/lmt-2018-0012