Fatty liver disease and the risk of erosive oesophagitis in the Korean population: a cross-sectional study

ObjectivesTo investigate an association between fatty liver disease (FLD) and erosive oesophagitis.Design and settingThis was a cross-sectional study of subjects selected from examinees who underwent health check-up, including oesophagogastroduodenoscopy in one hospital between 2004 and 2011. Erosiv...

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Bibliographic Details
Published in:BMJ open 2019-01, Vol.9 (1), p.e023585-e023585
Main Authors: Choi, Ja Sung, Kim, Hee Man, Yang, Yun-Jung, Lee, Sangheun, Jeong, Seok-Hoo, Han, Ki Jun
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Alcohol use
Blood pressure
Body mass index
Cross-Sectional Studies
Diabetes
Epidemiology
Esophagitis - epidemiology
Esophagitis - etiology
Family medical history
Fasting
Fatty Liver - epidemiology
Female
Gastroenterology and Hepatology
Gastroesophageal reflux
Gastrointestinal surgery
Humans
Hypertension
Laboratories
Liver cancer
Liver diseases
Male
Metabolic syndrome
Middle Aged
Obesity
Obesity - epidemiology
Republic of Korea - epidemiology
Risk Factors
Sex Distribution
Statistical analysis
Systematic review
Ultrasonic imaging
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Summary:ObjectivesTo investigate an association between fatty liver disease (FLD) and erosive oesophagitis.Design and settingThis was a cross-sectional study of subjects selected from examinees who underwent health check-up, including oesophagogastroduodenoscopy in one hospital between 2004 and 2011. Erosive oesophagitis was classified according to the Los Angeles classification and FLD was diagnosed with ultrasonography. The anthropometric and laboratory data of the subjects were analysed using χ2 test and multivariate logistic regression. Additionally, we have analysed our data with two-stage least square estimation using the Baltagi-Chang one-way model to clarify unobserved confounding variable.Primary outcome measureThe effect of FLD on erosive oesophagitis.ResultsAmong the 14 723 eligible subjects, 4232 (28.7%) subjects diagnosed with FLD were classified into the fatty liver group and 10 491 (71.3%) subjects without FLD were classified into the non-fatty liver group. The incidence rate of erosive oesophagitis was significantly higher in the fatty liver group than in the non-fatty liver group (10.4%vs6.1%, p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2018-023585