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Unsupervised feature extraction of anterior chamber OCT images for ordering and classification

We propose an image processing method for ordering anterior chamber optical coherence tomography (OCT) images in a fully unsupervised manner. The method consists of three steps: Firstly we preprocess the images (filtering the noise, aligning and normalizing the resolution); secondly, a distance meas...

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Bibliographic Details
Published in:Scientific reports 2019-02, Vol.9 (1), p.1157-1157, Article 1157
Main Authors: Amil, Pablo, González, Laura, Arrondo, Elena, Salinas, Cecilia, Guell, J. L., Masoller, Cristina, Parlitz, Ulrich
Format: Article
Language:English
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Summary:We propose an image processing method for ordering anterior chamber optical coherence tomography (OCT) images in a fully unsupervised manner. The method consists of three steps: Firstly we preprocess the images (filtering the noise, aligning and normalizing the resolution); secondly, a distance measure between images is computed for every pair of images; thirdly we apply a machine learning algorithm that exploits the distance measure to order the images in a two-dimensional plane. The method is applied to a large (~1000) database of anterior chamber OCT images of healthy subjects and patients with angle-closure and the resulting unsupervised ordering and classification is validated by two ophthalmologists.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-38136-8