Increased Serum CA125 and Brain-Derived Neurotrophic Factor (BDNF) Levels on Acute Myocardial Infarction: A Predictor for Acute Heart Failure

BACKGROUND This study was conducted to see whether increased values of serum CA125 and BDNF (brain-derived neurotrophic factor) on acute myocardial infarction (AMI) act as predictor for acute heart failure (AHF). MATERIAL AND METHODS Seventy-eight patients with clinically diagnosed cardiac function...

Full description

Saved in:
Bibliographic Details
Published in:Medical science monitor 2019-02, Vol.25, p.913-919
Main Authors: Wu, Haibo, Cao, Guangyun, Wang, Yuncan, Tian, Huanping, Du, Rongpin
Format: Article
Language:English
Subjects:
Clinical Research
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:BACKGROUND This study was conducted to see whether increased values of serum CA125 and BDNF (brain-derived neurotrophic factor) on acute myocardial infarction (AMI) act as predictor for acute heart failure (AHF). MATERIAL AND METHODS Seventy-eight patients with clinically diagnosed cardiac function II-IV; and AHF were considered as the study group of this retrospective study and patients who had cardiac function I (without AHF) were considered the control group (n=82). The values of CA125 and BDNF were measured using enzyme-linked immunosorbent assay (ELISA) for developing the correlation with the Killip classification, and the diagnostic value of AHF. RESULTS Statistically insignificant difference was noticed between baseline information e.g., blood pressure or smoking status of participants in study group and control group (P>0.05). The higher values of CA125 (5.68±1.8 U/mL or BDNF (19.48±5.3 pg/mL) in the study group had advantage over the control after independent sample t-test (P
ISSN:1643-3750
1234-1010
1643-3750
DOI:10.12659/MSM.912642