Glioblastoma and prolactinoma: a rare simultaneous occurrence

Abstract The simultaneous development of two or more primary central nervous system (CNS) tumors of different cell types represents 0.9% of all diagnosed CNS tumors. To the best of our knowledge, the simultaneous occurrence of glioblastoma and pituitary adenomas has been reported four times in the E...

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Bibliographic Details
Published in:Journal of surgical case reports 2019-02, Vol.2019 (2), p.rjz030
Main Authors: Alshalawi, Abdulaziz, Alkhaibary, Ali, Basalamah, Ali, Alassiri, Ali H, Alarifi, Abdulaziz
Format: Article
Language:English
Subjects:
Case Report
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Summary:Abstract The simultaneous development of two or more primary central nervous system (CNS) tumors of different cell types represents 0.9% of all diagnosed CNS tumors. To the best of our knowledge, the simultaneous occurrence of glioblastoma and pituitary adenomas has been reported four times in the English literature, with only two cases harboring prolactinoma and glioblastoma. We report a case of a 42-year-old male who was diagnosed with a sporadic co-occurrence of glioblastoma and a prolactin-secreting pituitary adenoma (prolactinoma). This case report discusses the clinical presentation, radiological/histopathological features, and outcome as well as reviewing the pertinent medical literature. Glioblastoma and a prolactin-secreting adenoma may be detected within the same patient. Further studies are required to delineate the tumorigenesis of the development and co-occurrence of multiple intracranial tumors.
ISSN:2042-8812
2042-8812
DOI:10.1093/jscr/rjz030