Factors associated with development of nephrotoxicity in patients treated with vancomycin versus daptomycin for severe Gram-positive infections: A practice-based study

To evaluate nephrotoxicity development in patients treated with vancomycin (VAN) and daptomycin (DAP) for proven severe Gram-positive infections in daily practice. A practice-based, observational, retrospective study (eight Spanish hospitals) was performed including patients ≥18 years with a baselin...

Full description

Saved in:
Bibliographic Details
Published in:Revista española de quimioterapia 2019-02, Vol.32 (1), p.22-30
Main Authors: Barberan, J, Mensa, J, Artero, A, Epelde, F, Rodriguez, J C, Ruiz-Morales, J, Calleja, J L, Guerra, J M, Martínez-Gil, I, Giménez, M J, Granizo, J J, Aguilar, L
Format: Article
Language:English
Subjects:
Original
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To evaluate nephrotoxicity development in patients treated with vancomycin (VAN) and daptomycin (DAP) for proven severe Gram-positive infections in daily practice. A practice-based, observational, retrospective study (eight Spanish hospitals) was performed including patients ≥18 years with a baseline glomerular filtration rate (GFR)>30 mL/min and/or serum creatinine level48h. Nephrotoxicity was considered as a decrease in baseline GRF to 10 mL/min from a baseline GRF
ISSN:0214-3429
1988-9518