Kidney Stones and Risk of Osteoporotic Fracture in Chronic Kidney Disease

Osteoporotic fracture associated with calcium dysregulation is more common in patients with kidney stones. However, little is known about the association of kidney stones and bone health status in patients with chronic kidney disease (CKD). This retrospective medical record-based study included 2282...

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Bibliographic Details
Published in:Scientific reports 2019-02, Vol.9 (1), p.1929-1929, Article 1929
Main Authors: Han, Seung Gyu, Oh, Jieun, Jeon, Hee Jung, Park, Chan, Cho, Jeonghwan, Shin, Dong Ho
Format: Article
Language:English
Subjects:
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Body mass index
Calcium
Calculi
Fractures
Glomerular filtration rate
Humanities and Social Sciences
Kidney diseases
Kidney stones
Kidneys
multidisciplinary
Nephrolithiasis
Osteoporosis
Risk factors
Science
Science (multidisciplinary)
Smoking
Surgeons General
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Summary:Osteoporotic fracture associated with calcium dysregulation is more common in patients with kidney stones. However, little is known about the association of kidney stones and bone health status in patients with chronic kidney disease (CKD). This retrospective medical record-based study included 2282 patients with stable stage 3–4 CKD between 2007 and 2017. Of these, 113 patients were diagnosed with kidney stones. Propensity score matching for 226 patients with and without kidney stones showed that osteoporotic fracture occurred more often in patients with kidney stones (33, 29.2%) than in patients without kidney stones (16, 14.2%), resulting in rates of 5.56 and 2.63/100 patient-years, respectively (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-38191-1