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Emergence of divergent enterovirus (EV) D68 sub-clade D1 strains, northern Italy, September to October 2018

Between September and October 2018, an enterovirus D68 (EV-D68) outbreak occurred in patients hospitalised with severe acute respiratory infection in northern Italy; 21 laboratory-confirmed cases were reported. Phylogenetic analysis revealed that 16/20 of the EV-D68 sequences belonged to a divergent...

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Published in:Euro surveillance : bulletin européen sur les maladies transmissibles 2019-02, Vol.24 (7)
Main Authors: Pellegrinelli, Laura, Giardina, Federica, Lunghi, Giovanna, Uceda Renteria, Sara Colonia, Greco, Letizia, Fratini, Alice, Galli, Cristina, Piralla, Antonio, Binda, Sandro, Pariani, Elena, Baldanti, Fausto
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Language:English
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Summary:Between September and October 2018, an enterovirus D68 (EV-D68) outbreak occurred in patients hospitalised with severe acute respiratory infection in northern Italy; 21 laboratory-confirmed cases were reported. Phylogenetic analysis revealed that 16/20 of the EV-D68 sequences belonged to a divergent group within the sub-clade D1. Since its upsurge, EV-D68 has undergone rapid evolution with the emergence of new viral variants, emphasising the need for molecular surveillance that include outpatients with respiratory illness.
ISSN:1560-7917
1025-496X
1560-7917
DOI:10.2807/1560-7917.es.2018.24.7.1900090