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Merkel cells: A collective review of current concepts

Merkel cells (MCs) constitute a very unique population of postmitotic cells scattered along the dermo-epidermal junction. These cells that have synaptic contacts with somatosensory afferents are regarded to have a pivotal role in sensory discernment. Several concerns exist till date as to their orig...

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Bibliographic Details
Published in:International journal of applied and basic medical research 2019-01, Vol.9 (1), p.9-13
Main Authors: Abraham, Jacob, Mathew, Sherin
Format: Article
Language:English
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Summary:Merkel cells (MCs) constitute a very unique population of postmitotic cells scattered along the dermo-epidermal junction. These cells that have synaptic contacts with somatosensory afferents are regarded to have a pivotal role in sensory discernment. Several concerns exist till date as to their origin, multiplication, and relevance in skin biology. The article, a collective review of literature extracted from PubMed search and dermatology books, provides novel insights into the physiology of MCs and their recent advances.
ISSN:2229-516X
2248-9606
DOI:10.4103/ijabmr.IJABMR_34_18