Treatment of Posaconazole-Induced Peripheral Neuropathy With Methylprednisolone and Magnesium Infusions: A Case Report

Abstract The tolerability of long-term posaconazole use remains poorly defined. We present a patient who developed peripheral neuropathy following long-term exposure to the tablet formulation of posaconazole, which was treated with methylprednisolone and magnesium infusions. The potential role of me...

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Bibliographic Details
Published in:Open forum infectious diseases 2019-02, Vol.6 (2), p.ofz031-ofz031
Main Authors: Hussain, Sadia, Nissen, Susan, Holland, Steven M, Sandroni, Paola, Lionakis, Michail S
Format: Article
Language:English
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Brief Report
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Summary:Abstract The tolerability of long-term posaconazole use remains poorly defined. We present a patient who developed peripheral neuropathy following long-term exposure to the tablet formulation of posaconazole, which was treated with methylprednisolone and magnesium infusions. The potential role of methylprednisolone and magnesium infusions in managing this potentially irreversible triazole-associated complication requires further study.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofz031