Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has been a remarkable increase in approved nano-based pharmaceutical products. These novel nano-based systems can either be therapeutic agents themselves, or else act as vehicles to carry different active pharmaceutica...

Full description

Saved in:
Bibliographic Details
Published in:Nanomedicine (London, England) England), 2019-01, Vol.14 (1), p.93-126
Main Authors: Farjadian, Fatemeh, Ghasemi, Amir, Gohari, Omid, Roointan, Amir, Karimi, Mahdi, Hamblin, Michael R
Format: Article
Language:English
Subjects:
Chemistry, Pharmaceutical - methods
drug delivery
Drug Delivery Systems - methods
Excipients - chemistry
Humans
Industrial development
Legislation, Drug
Liposomes - chemistry
market size
Metals - chemistry
nanocrystal
nanodrug
nanoliposome
nanomedicine
Nanomedicine - methods
Nanoparticles
Nanoparticles - chemistry
nanopharmaceuticals
nanopolymer
nanotechnology
Polymers - chemistry
Regulatory approval
Review
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has been a remarkable increase in approved nano-based pharmaceutical products. These novel nano-based systems can either be therapeutic agents themselves, or else act as vehicles to carry different active pharmaceutical agents into specific parts of the body. Currently marketed nanostructures include nanocrystals, liposomes and lipid nanoparticles, PEGylated polymeric nanodrugs, other polymers, protein-based nanoparticles and metal-based nanoparticles. A range of issues must be addressed in the development of these nanostructures. Ethics, market size, possibility of market failure, costs and commercial development, are some topics which are on the table to be discussed. After passing all the ethical and biological assessments, and satisfying the investors as to future profitability, only a handful of these nanoformulations, successfully obtained marketing approval. We survey the range of nanomedicines that have received regulatory approval and are marketed. We discuss ethics, costs, commercial development and possible market failure. We estimate the global nanomedicine market size and future growth. Our goal is to summarize the different approved nanoformulations on the market, and briefly cover the challenges and future outlook.
ISSN:1743-5889
1748-6963
1748-6963
DOI:10.2217/nnm-2018-0120