Diabetes Prevalence Survey of Pakistan (DPS-PAK): prevalence of type 2 diabetes mellitus and prediabetes using HbA1c: a population-based survey from Pakistan

ObjectivesWe conducted a Pakistan-wide community-based survey on the prevalence of type 2 diabetes using glycated haemoglobin (HbA1c) as the screening test. The aim was to estimate diabetes prevalence across different demographic groups as well as all regions of Pakistan.Design, settings and partici...

Full description

Saved in:
Bibliographic Details
Published in:BMJ open 2019-02, Vol.9 (2), p.e025300-e025300
Main Authors: Aamir, Azizul Hasan, Ul-Haq, Zia, Mahar, Saeed A, Qureshi, Faisal Masood, Ahmad, Ibrar, Jawa, Ali, Sheikh, Aisha, Raza, Abbas, Fazid, Sheraz, Jadoon, Zahid, Ishtiaq, Osama, Safdar, Nauman, Afridi, Hussain, Heald, Adrian H
Format: Article
Language:English
Subjects:
Adult
Anemia
Blood Glucose - analysis
Body Mass Index
Censuses
Cross-Sectional Studies
Diabetes
Diabetes and Endocrinology
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - epidemiology
Fasting
Female
Glucose
Glucose Tolerance Test
Glycated Hemoglobin A - analysis
Hemoglobin
Humans
Logistic Models
Low income groups
Male
Mass Screening - methods
Middle Aged
Obesity
Obesity - complications
Pakistan - epidemiology
Population
Prediabetic State - blood
Prediabetic State - epidemiology
Prevalence
Provinces
Public health
ROC Curve
Rural areas
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ObjectivesWe conducted a Pakistan-wide community-based survey on the prevalence of type 2 diabetes using glycated haemoglobin (HbA1c) as the screening test. The aim was to estimate diabetes prevalence across different demographic groups as well as all regions of Pakistan.Design, settings and participantsMultistaged stratified cluster sampling was used for the representative selection of people aged ≥20 years, residing in 378 sampled clusters of 16 randomly selected districts, in this cross-sectional study. Eligible participants had blood drawn for HbA1c analyses at field clinics near to their homes. The oral glucose tolerance test (OGTT) was conducted on a subsample of the participants. Overall and stratified prevalence of type 2 diabetes and its association with risk factors were estimated using logistic regression models.Main outcome measuresPrevalence of prediabetes and type 2 diabetes.ResultsOf 18 856 eligible participants the prevalence of prediabetes was 10.91% (95% CI 10.46 to 11.36, n=2057) and type 2 diabetes was 16.98% (95% CI 16.44 to 17.51, n=3201). Overall, the mean HbA1c level was 5.62% (SD 1.96), and among newly diagnosed was 8.56% (SD 2.08). The prevalence was highest in age 51–60 years (26.03%, p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2018-025300