Benefits of Vitamins in the Treatment of Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease in the elderly, which is clinically characterized by bradykinesia, resting tremor, abnormal posture balance, and hypermyotonia. Currently, the pathogenic mechanism of PD remains unclear. Numerous clinical studies as well as...

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Bibliographic Details
Published in:Oxidative medicine and cellular longevity 2019-01, Vol.2019 (2019), p.1-14
Main Authors: Su, Yana, Jiang, Xue, Li, Chunxiao, Zhang, Ming, Zhao, Xiuzhen, Zhang, Ying
Format: Article
Language:English
Subjects:
Animals
Clinical Trials as Topic
Humans
Neurosciences
Oxidation
Oxidative Stress
Parkinson Disease - drug therapy
Parkinson Disease - pathology
Parkinson's disease
Review
Vitamin D
Vitamin deficiency
Vitamins - therapeutic use
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Summary:Parkinson’s disease (PD) is the second most common neurodegenerative disease in the elderly, which is clinically characterized by bradykinesia, resting tremor, abnormal posture balance, and hypermyotonia. Currently, the pathogenic mechanism of PD remains unclear. Numerous clinical studies as well as animal and cell experiments have found a certain relationship between the vitamin family and PD. The antioxidant properties of vitamins and their biological functions of regulating gene expression may be beneficial for the treatment of PD. Current clinical evidence indicates that proper supplementation of various vitamins can reduce the incidence of PD in the general population and improve the clinical symptoms of patients with PD; nevertheless, the safety of regular vitamin supplements still needs to be highlighted. Vitamin supplementation may be an effective adjuvant treatment for PD. In this review, we summarized the biological correlations between vitamins and PD as well as the underlying pathophysiological mechanisms. Additionally, we elaborated the therapeutic potentials of vitamins for PD.
ISSN:1942-0900
1942-0994
DOI:10.1155/2019/9426867