Head trauma complicated with primary cranial vault lymphoma: A case report

Primary cranial vault lymphoma (PCVL) is an extremely rare extranodal lymphoma in the skull. This case study investigates the clinical features, so as to improve the understanding of the diagnosis and therapy. A 31-year-old male presented painful scalp mass at the site of 1-month-old head trauma. Th...

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Bibliographic Details
Published in:Medicine (Baltimore) 2019-02, Vol.98 (7), p.e14465-e14465
Main Authors: Huang, Jie, Tang, Dong, Xu, Yan, Wang, Xuna, Yu, Chuanwen, Dong, Yang
Format: Article
Language:English
Subjects:
Adult
Clinical Case Report
Craniocerebral Trauma - complications
Craniocerebral Trauma - pathology
Humans
Male
Plasmablastic Lymphoma - etiology
Plasmablastic Lymphoma - pathology
Scalp - injuries
Scalp - pathology
Skull Neoplasms - etiology
Skull Neoplasms - pathology
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Summary:Primary cranial vault lymphoma (PCVL) is an extremely rare extranodal lymphoma in the skull. This case study investigates the clinical features, so as to improve the understanding of the diagnosis and therapy. A 31-year-old male presented painful scalp mass at the site of 1-month-old head trauma. The final diagnosis was plasma cell lymphoma, which is a rare subtype of diffuse large B-cell lymphoma based on biopsy and immunohistochemistry findings. The patient received total tumor resection in combination with chemotherapy OUTCOMES:: The patient survived without signs of systemic dissemination for 12 months after surgery at the time of last follow-up. Trauma may be one of the factors that induce PCVL. The final diagnosis of PCVL depends on pathology and immunohistochemistry findings. A combined treatment of surgery, chemotherapy, and radiotherapy can achieve favorable outcomes.
ISSN:0025-7974
1536-5964
1536-5964
DOI:10.1097/MD.0000000000014465