Staphylococcus aureus : an underestimated factor in the pathogenesis of atopic dermatitis?

Atopic dermatitis is a common, recurrent pruritic dermatosis with a complex pathogenesis. It has been associated with disordered patterns of immunological response and impaired epithelial barrier integrity. These features predispose the patients to robust colonization of skin lesions by . Virulence...

Full description

Saved in:
Bibliographic Details
Published in:Postȩpy dermatologii i alergologii 2019-02, Vol.36 (1), p.11-17
Main Authors: Blicharz, Leszek, Rudnicka, Lidia, Samochocki, Zbigniew
Format: Article
Language:English
Subjects:
Review Paper
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Atopic dermatitis is a common, recurrent pruritic dermatosis with a complex pathogenesis. It has been associated with disordered patterns of immunological response and impaired epithelial barrier integrity. These features predispose the patients to robust colonization of skin lesions by . Virulence factors of (e.g. superantigens, α- and δ-toxin, protein A) have been shown to exacerbate and perpetuate the course of atopic dermatitis. Novel therapeutic options with potential for restoring natural microbiome composition are being elaborated and may enter clinical practice in the future.
ISSN:1642-395X
2299-0046
DOI:10.5114/ada.2019.82821