The role of surgical resection before palliative chemotherapy in advanced gastric cancer

The role of palliative surgical resection in recurrent or metastatic gastric cancer is still controversial. A retrospective review was conducted on 689 patients who received palliative chemotherapy for recurrent (n = 307) or primary metastatic (n = 382) gastric cancer. Among 131 patients (89 primary...

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Bibliographic Details
Published in:Scientific reports 2019-03, Vol.9 (1), p.4136-4136, Article 4136
Main Authors: Choi, Yong Won, Ahn, Mi Sun, Jeong, Geum Sook, Lee, Hyun Woo, Jeong, Seong Hyun, Kang, Seok Yun, Park, Joon Seong, Choi, Jin-Hyuk, Son, Sang-Yong, Hur, Hoon, Han, Sang-Uk, Sheen, Seung Soo
Format: Article
Language:English
Subjects:
631/67/1504/1829
692/4028/67/1504/1829
Aged
Antineoplastic Agents - therapeutic use
Chemotherapy
Female
Gastrectomy
Gastrectomy - adverse effects
Gastrectomy - methods
Gastric cancer
Humanities and Social Sciences
Humans
Male
Metastases
Metastasis
multidisciplinary
Multivariate analysis
Neoplasm Metastasis
Palliation
Palliative Care - methods
Postoperative Complications - epidemiology
Science
Science (multidisciplinary)
Stomach Neoplasms - drug therapy
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Survival Analysis
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Summary:The role of palliative surgical resection in recurrent or metastatic gastric cancer is still controversial. A retrospective review was conducted on 689 patients who received palliative chemotherapy for recurrent (n = 307) or primary metastatic (n = 382) gastric cancer. Among 131 patients (89 primary metastatic and 42 recurrent) with surgical resection before chemotherpay, 75 underwent gastrectomy, 42 metastasectomy, and 14 gastrectomy with metastasectomy. The median overall survival (OS) of patients who underwent surgical resection was significantly longer than that of patients who received chemotherapy alone (18 vs. 9 months, p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-39432-7