Predictors of isoniazid preventive therapy completion among adults newly diagnosed with HIV in rural Malawi

SETTING: To reduce the risk of tuberculosis (TB) among individuals with human immunodeficiency virus (HIV) infection, the World Health Organization recommends at least 6 months of isoniazid preventive therapy (IPT). Completion of IPT remains a major challenge in resource-limited settings.OBJECTIVE:...

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Bibliographic Details
Published in:The international journal of tuberculosis and lung disease 2018-04, Vol.22 (4), p.371-377
Main Authors: Little, K. M., Khundi, M., Barnes, G. L., Ngwira, L. G., Nkhoma, A., Makombe, S., Corbett, E. L., Chaisson, R. E., Dowdy, D. W.
Format: Article
Language:English
Subjects:
Adults
Co-Infection
Females
HIV
Human immunodeficiency virus
IPT
Isoniazid
Males
Regression models
Therapy
Tuberculosis
Viruses
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Summary:SETTING: To reduce the risk of tuberculosis (TB) among individuals with human immunodeficiency virus (HIV) infection, the World Health Organization recommends at least 6 months of isoniazid preventive therapy (IPT). Completion of IPT remains a major challenge in resource-limited settings.OBJECTIVE: To evaluate predictors of IPT completion in individuals newly diagnosed with HIV.DESIGN: Predictors of IPT completion among adults newly diagnosed with HIV in rural Malawi were evaluated using a multilevel logistic regression model.RESULTS: Of 974 participants who screened negative for active TB and were started on IPT, 732 (75%) completed treatment. Only one IPT-eligible individual refused treatment. Participants who were aged
ISSN:1027-3719
1815-7920
DOI:10.5588/ijtld.16.0836