Acquired Gitelman Syndrome Associated with Systemic Sclerosis

Gitelman syndrome is an inherited renal disorder characterized by hypomagnesemia, hypokalemia, hypocalciuria and metabolic alkalosis linked to the genes encoding the thiazide sensitive NaCl cotransporter (NCCT) located on the distal convoluted tubule of the kidney. It usually presents in late childh...

Full description

Saved in:
Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2019-01, Vol.11 (1), p.e3923
Main Authors: Masab, Muhammad, Goyal, Abhinav, Abrol, Surbhi, Rangaswami, Janani
Format: Article
Language:English
Subjects:
Autoimmune diseases
Case reports
Dysphagia
Electrolytes
Family medical history
Hypertension
Internal Medicine
Metabolism
Muscle pain
Mutation
Nephrology
Potassium
Scleroderma
Systemic sclerosis
Urine
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Gitelman syndrome is an inherited renal disorder characterized by hypomagnesemia, hypokalemia, hypocalciuria and metabolic alkalosis linked to the genes encoding the thiazide sensitive NaCl cotransporter (NCCT) located on the distal convoluted tubule of the kidney. It usually presents in late childhood or early adulthood with electrolyte abnormalities resembling chronic thiazide diuretic use. Acquired Gitelman syndrome is a very rare disorder mostly associated with Sjogren's syndrome.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.3923