Loading…
Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study
Myocardial perfusion imaging (MPI) is considered useful for risk stratification among patients with chronic kidney disease (CKD), without renal deterioration by contrast media. The Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS 3) is a multicenter, pro...
Saved in:
| Published in: | Journal of nuclear cardiology 2019-04, Vol.26 (2), p.431-440 |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c522t-463439cd07d31d87a00c02b982cef3a14849b7cbdeaa72cc3d25d3d4500cef443 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c522t-463439cd07d31d87a00c02b982cef3a14849b7cbdeaa72cc3d25d3d4500cef443 |
| container_end_page | 440 |
| container_issue | 2 |
| container_start_page | 431 |
| container_title | Journal of nuclear cardiology |
| container_volume | 26 |
| creator | Nakamura, Satoko Kawano, Yuhei Nakajima, Kenichi Hase, Hiroki Joki, Nobuhiko Hatta, Tsuguru Nishimura, Shigeyuki Moroi, Masao Nakagawa, Susumu Kasai, Tokuo Kusuoka, Hideo Takeishi, Yasuchika Momose, Mitsuru Takehana, Kazuya Nanasato, Mamoru Yoda, Syunichi Nishina, Hidetaka Matsumoto, Naoya Nishimura, Tsunehiko |
| description | Myocardial perfusion imaging (MPI) is considered useful for risk stratification among patients with chronic kidney disease (CKD), without renal deterioration by contrast media.
The Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS 3) is a multicenter, prospective cohort study investigating the ability of MPI to predict cardiac events in 529 CKD patients without a definitive coronary artery disease. All patients were assessed by stress and rest MPI with 99mTc-tetrofosmin and data were analyzed using a defect scoring method and QGS software. Major cardiac events were analyzed for 3 years after registration. The mean eGFR was 29.0 ± 12.8 (mL/minute/1.73 m2). The mean summed stress/rest/difference (SSS, SRS, SDS) scores were 1.9 ± 3.8, 1.1 ± 3.0, and 0.8 ± 1.8, respectively. A total of 60 cardiac events (three cardiac deaths, six sudden deaths, five nonfatal myocardial infarctions, 46 hospitalization cases for heart failure) occurred. The event-free survival rate was lower among patients with kidney dysfunction, higher SSS, and higher CRP values. Multivariate Cox regression analysis independently associated SSS ≥8, eGFR |
| doi_str_mv | 10.1007/s12350-017-0880-5 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6430747</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S107135812306107X</els_id><sourcerecordid>1891896484</sourcerecordid><originalsourceid>FETCH-LOGICAL-c522t-463439cd07d31d87a00c02b982cef3a14849b7cbdeaa72cc3d25d3d4500cef443</originalsourceid><addsrcrecordid>eNp9Ul1rFDEUHUSxtfoDfJGAL76k5mM-FYSybKulYKH6HLLJndnU3WRNMivzo_yPvevUoi-FQELuOSfn5N6ieM3ZKWeseZ-4kBWjjDeUtS2j1ZPimFdS0Lqq-FM8s4ZTWbX8qHiR0i1jrJNd97w4Em0pu6Zmx8Xv6xgGH1J2hqQ82omEnhgdrdOGwB58TsR5cql32kMCstPZ_bn85fKamHUMHpk_nPUwEesSaASNyfmBLBcXdNAZLNlOYZbckGuIPZaDJ26rB4R9IOfOY0HSCXQkEXYh5oOJvAZySc8Wi-XNDZGzuZfFs15vEry630-K7-fLb4vP9OrrxZfF2RU1lRCZlrXEfMayxkpu20YzZphYda0w0EvNy7bsVo1ZWdC6EcZIKyorbVkhDvqylCfFp1l3N662YA0mjnqjdhFNx0kF7dT_Fe_Wagh7VZeSNWWDAm9ngcPPqmRcBrM2wXswWQnR1YIziah398_E8HOElNXWJQObDf51GJPibYerRrsI5TPUxJBShP7BDGfqMAxqHgaFw6AOw6Aq5Lz5N8UD42_3ESBmQMKSHyCq2zBG7EZ6VPXjTAJswN4hCeOBN2BdPKSzwT3CvgNxY9VM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1891896484</pqid></control><display><type>article</type><title>Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study</title><source>Springer Link</source><creator>Nakamura, Satoko ; Kawano, Yuhei ; Nakajima, Kenichi ; Hase, Hiroki ; Joki, Nobuhiko ; Hatta, Tsuguru ; Nishimura, Shigeyuki ; Moroi, Masao ; Nakagawa, Susumu ; Kasai, Tokuo ; Kusuoka, Hideo ; Takeishi, Yasuchika ; Momose, Mitsuru ; Takehana, Kazuya ; Nanasato, Mamoru ; Yoda, Syunichi ; Nishina, Hidetaka ; Matsumoto, Naoya ; Nishimura, Tsunehiko</creator><creatorcontrib>Nakamura, Satoko ; Kawano, Yuhei ; Nakajima, Kenichi ; Hase, Hiroki ; Joki, Nobuhiko ; Hatta, Tsuguru ; Nishimura, Shigeyuki ; Moroi, Masao ; Nakagawa, Susumu ; Kasai, Tokuo ; Kusuoka, Hideo ; Takeishi, Yasuchika ; Momose, Mitsuru ; Takehana, Kazuya ; Nanasato, Mamoru ; Yoda, Syunichi ; Nishina, Hidetaka ; Matsumoto, Naoya ; Nishimura, Tsunehiko</creatorcontrib><description>Myocardial perfusion imaging (MPI) is considered useful for risk stratification among patients with chronic kidney disease (CKD), without renal deterioration by contrast media.
The Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS 3) is a multicenter, prospective cohort study investigating the ability of MPI to predict cardiac events in 529 CKD patients without a definitive coronary artery disease. All patients were assessed by stress and rest MPI with 99mTc-tetrofosmin and data were analyzed using a defect scoring method and QGS software. Major cardiac events were analyzed for 3 years after registration. The mean eGFR was 29.0 ± 12.8 (mL/minute/1.73 m2). The mean summed stress/rest/difference (SSS, SRS, SDS) scores were 1.9 ± 3.8, 1.1 ± 3.0, and 0.8 ± 1.8, respectively. A total of 60 cardiac events (three cardiac deaths, six sudden deaths, five nonfatal myocardial infarctions, 46 hospitalization cases for heart failure) occurred. The event-free survival rate was lower among patients with kidney dysfunction, higher SSS, and higher CRP values. Multivariate Cox regression analysis independently associated SSS ≥8, eGFR <15 (mL/minute/1.73 m2), and CRP ≥0.3 (mg/dL) with cardiac events.
Together with eGFR and CRP, MPI can predict cardiac events in patients with CKD.</description><identifier>ISSN: 1071-3581</identifier><identifier>ISSN: 1532-6551</identifier><identifier>EISSN: 1532-6551</identifier><identifier>DOI: 10.1007/s12350-017-0880-5</identifier><identifier>PMID: 28439760</identifier><language>eng</language><publisher>Cham: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; C-reactive protein ; Cardiology ; Cardiovascular morbidity ; CONTRAST MEDIA ; CORONARIES ; DISEASE INCIDENCE ; Disease-Free Survival ; Electrocardiography ; estimated glomerular filtration rate ; Female ; Glomerular Filtration Rate ; HAZARDS ; HEART FAILURE ; Humans ; Imaging ; Japan ; Kidney Failure, Chronic - diagnostic imaging ; KIDNEYS ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Multivariate Analysis ; MYOCARDIAL INFARCTION ; Myocardial Perfusion Imaging ; Nuclear Medicine ; Original ; Original Article ; PATIENTS ; Prognosis ; Proportional Hazards Models ; Prospective Studies ; Radiology ; RADIOLOGY AND NUCLEAR MEDICINE ; REGRESSION ANALYSIS ; Risk ; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY ; Software ; TECHNETIUM 99 ; Tomography, Emission-Computed, Single-Photon ; Treatment Outcome</subject><ispartof>Journal of nuclear cardiology, 2019-04, Vol.26 (2), p.431-440</ispartof><rights>2019 THE AUTHORS. Published by ELSEVIER INC. on behalf of American Society of Nuclear Cardiology</rights><rights>The Author(s) 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c522t-463439cd07d31d87a00c02b982cef3a14849b7cbdeaa72cc3d25d3d4500cef443</citedby><cites>FETCH-LOGICAL-c522t-463439cd07d31d87a00c02b982cef3a14849b7cbdeaa72cc3d25d3d4500cef443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28439760$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/22962103$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakamura, Satoko</creatorcontrib><creatorcontrib>Kawano, Yuhei</creatorcontrib><creatorcontrib>Nakajima, Kenichi</creatorcontrib><creatorcontrib>Hase, Hiroki</creatorcontrib><creatorcontrib>Joki, Nobuhiko</creatorcontrib><creatorcontrib>Hatta, Tsuguru</creatorcontrib><creatorcontrib>Nishimura, Shigeyuki</creatorcontrib><creatorcontrib>Moroi, Masao</creatorcontrib><creatorcontrib>Nakagawa, Susumu</creatorcontrib><creatorcontrib>Kasai, Tokuo</creatorcontrib><creatorcontrib>Kusuoka, Hideo</creatorcontrib><creatorcontrib>Takeishi, Yasuchika</creatorcontrib><creatorcontrib>Momose, Mitsuru</creatorcontrib><creatorcontrib>Takehana, Kazuya</creatorcontrib><creatorcontrib>Nanasato, Mamoru</creatorcontrib><creatorcontrib>Yoda, Syunichi</creatorcontrib><creatorcontrib>Nishina, Hidetaka</creatorcontrib><creatorcontrib>Matsumoto, Naoya</creatorcontrib><creatorcontrib>Nishimura, Tsunehiko</creatorcontrib><title>Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study</title><title>Journal of nuclear cardiology</title><addtitle>J. Nucl. Cardiol</addtitle><addtitle>J Nucl Cardiol</addtitle><description>Myocardial perfusion imaging (MPI) is considered useful for risk stratification among patients with chronic kidney disease (CKD), without renal deterioration by contrast media.
The Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS 3) is a multicenter, prospective cohort study investigating the ability of MPI to predict cardiac events in 529 CKD patients without a definitive coronary artery disease. All patients were assessed by stress and rest MPI with 99mTc-tetrofosmin and data were analyzed using a defect scoring method and QGS software. Major cardiac events were analyzed for 3 years after registration. The mean eGFR was 29.0 ± 12.8 (mL/minute/1.73 m2). The mean summed stress/rest/difference (SSS, SRS, SDS) scores were 1.9 ± 3.8, 1.1 ± 3.0, and 0.8 ± 1.8, respectively. A total of 60 cardiac events (three cardiac deaths, six sudden deaths, five nonfatal myocardial infarctions, 46 hospitalization cases for heart failure) occurred. The event-free survival rate was lower among patients with kidney dysfunction, higher SSS, and higher CRP values. Multivariate Cox regression analysis independently associated SSS ≥8, eGFR <15 (mL/minute/1.73 m2), and CRP ≥0.3 (mg/dL) with cardiac events.
Together with eGFR and CRP, MPI can predict cardiac events in patients with CKD.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>C-reactive protein</subject><subject>Cardiology</subject><subject>Cardiovascular morbidity</subject><subject>CONTRAST MEDIA</subject><subject>CORONARIES</subject><subject>DISEASE INCIDENCE</subject><subject>Disease-Free Survival</subject><subject>Electrocardiography</subject><subject>estimated glomerular filtration rate</subject><subject>Female</subject><subject>Glomerular Filtration Rate</subject><subject>HAZARDS</subject><subject>HEART FAILURE</subject><subject>Humans</subject><subject>Imaging</subject><subject>Japan</subject><subject>Kidney Failure, Chronic - diagnostic imaging</subject><subject>KIDNEYS</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>MYOCARDIAL INFARCTION</subject><subject>Myocardial Perfusion Imaging</subject><subject>Nuclear Medicine</subject><subject>Original</subject><subject>Original Article</subject><subject>PATIENTS</subject><subject>Prognosis</subject><subject>Proportional Hazards Models</subject><subject>Prospective Studies</subject><subject>Radiology</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>REGRESSION ANALYSIS</subject><subject>Risk</subject><subject>SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY</subject><subject>Software</subject><subject>TECHNETIUM 99</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><subject>Treatment Outcome</subject><issn>1071-3581</issn><issn>1532-6551</issn><issn>1532-6551</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9Ul1rFDEUHUSxtfoDfJGAL76k5mM-FYSybKulYKH6HLLJndnU3WRNMivzo_yPvevUoi-FQELuOSfn5N6ieM3ZKWeseZ-4kBWjjDeUtS2j1ZPimFdS0Lqq-FM8s4ZTWbX8qHiR0i1jrJNd97w4Em0pu6Zmx8Xv6xgGH1J2hqQ82omEnhgdrdOGwB58TsR5cql32kMCstPZ_bn85fKamHUMHpk_nPUwEesSaASNyfmBLBcXdNAZLNlOYZbckGuIPZaDJ26rB4R9IOfOY0HSCXQkEXYh5oOJvAZySc8Wi-XNDZGzuZfFs15vEry630-K7-fLb4vP9OrrxZfF2RU1lRCZlrXEfMayxkpu20YzZphYda0w0EvNy7bsVo1ZWdC6EcZIKyorbVkhDvqylCfFp1l3N662YA0mjnqjdhFNx0kF7dT_Fe_Wagh7VZeSNWWDAm9ngcPPqmRcBrM2wXswWQnR1YIziah398_E8HOElNXWJQObDf51GJPibYerRrsI5TPUxJBShP7BDGfqMAxqHgaFw6AOw6Aq5Lz5N8UD42_3ESBmQMKSHyCq2zBG7EZ6VPXjTAJswN4hCeOBN2BdPKSzwT3CvgNxY9VM</recordid><startdate>20190401</startdate><enddate>20190401</enddate><creator>Nakamura, Satoko</creator><creator>Kawano, Yuhei</creator><creator>Nakajima, Kenichi</creator><creator>Hase, Hiroki</creator><creator>Joki, Nobuhiko</creator><creator>Hatta, Tsuguru</creator><creator>Nishimura, Shigeyuki</creator><creator>Moroi, Masao</creator><creator>Nakagawa, Susumu</creator><creator>Kasai, Tokuo</creator><creator>Kusuoka, Hideo</creator><creator>Takeishi, Yasuchika</creator><creator>Momose, Mitsuru</creator><creator>Takehana, Kazuya</creator><creator>Nanasato, Mamoru</creator><creator>Yoda, Syunichi</creator><creator>Nishina, Hidetaka</creator><creator>Matsumoto, Naoya</creator><creator>Nishimura, Tsunehiko</creator><general>Elsevier Inc</general><general>Springer International Publishing</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope><scope>5PM</scope></search><sort><creationdate>20190401</creationdate><title>Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study</title><author>Nakamura, Satoko ; Kawano, Yuhei ; Nakajima, Kenichi ; Hase, Hiroki ; Joki, Nobuhiko ; Hatta, Tsuguru ; Nishimura, Shigeyuki ; Moroi, Masao ; Nakagawa, Susumu ; Kasai, Tokuo ; Kusuoka, Hideo ; Takeishi, Yasuchika ; Momose, Mitsuru ; Takehana, Kazuya ; Nanasato, Mamoru ; Yoda, Syunichi ; Nishina, Hidetaka ; Matsumoto, Naoya ; Nishimura, Tsunehiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c522t-463439cd07d31d87a00c02b982cef3a14849b7cbdeaa72cc3d25d3d4500cef443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>C-reactive protein</topic><topic>Cardiology</topic><topic>Cardiovascular morbidity</topic><topic>CONTRAST MEDIA</topic><topic>CORONARIES</topic><topic>DISEASE INCIDENCE</topic><topic>Disease-Free Survival</topic><topic>Electrocardiography</topic><topic>estimated glomerular filtration rate</topic><topic>Female</topic><topic>Glomerular Filtration Rate</topic><topic>HAZARDS</topic><topic>HEART FAILURE</topic><topic>Humans</topic><topic>Imaging</topic><topic>Japan</topic><topic>Kidney Failure, Chronic - diagnostic imaging</topic><topic>KIDNEYS</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>MYOCARDIAL INFARCTION</topic><topic>Myocardial Perfusion Imaging</topic><topic>Nuclear Medicine</topic><topic>Original</topic><topic>Original Article</topic><topic>PATIENTS</topic><topic>Prognosis</topic><topic>Proportional Hazards Models</topic><topic>Prospective Studies</topic><topic>Radiology</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>REGRESSION ANALYSIS</topic><topic>Risk</topic><topic>SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY</topic><topic>Software</topic><topic>TECHNETIUM 99</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakamura, Satoko</creatorcontrib><creatorcontrib>Kawano, Yuhei</creatorcontrib><creatorcontrib>Nakajima, Kenichi</creatorcontrib><creatorcontrib>Hase, Hiroki</creatorcontrib><creatorcontrib>Joki, Nobuhiko</creatorcontrib><creatorcontrib>Hatta, Tsuguru</creatorcontrib><creatorcontrib>Nishimura, Shigeyuki</creatorcontrib><creatorcontrib>Moroi, Masao</creatorcontrib><creatorcontrib>Nakagawa, Susumu</creatorcontrib><creatorcontrib>Kasai, Tokuo</creatorcontrib><creatorcontrib>Kusuoka, Hideo</creatorcontrib><creatorcontrib>Takeishi, Yasuchika</creatorcontrib><creatorcontrib>Momose, Mitsuru</creatorcontrib><creatorcontrib>Takehana, Kazuya</creatorcontrib><creatorcontrib>Nanasato, Mamoru</creatorcontrib><creatorcontrib>Yoda, Syunichi</creatorcontrib><creatorcontrib>Nishina, Hidetaka</creatorcontrib><creatorcontrib>Matsumoto, Naoya</creatorcontrib><creatorcontrib>Nishimura, Tsunehiko</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of nuclear cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakamura, Satoko</au><au>Kawano, Yuhei</au><au>Nakajima, Kenichi</au><au>Hase, Hiroki</au><au>Joki, Nobuhiko</au><au>Hatta, Tsuguru</au><au>Nishimura, Shigeyuki</au><au>Moroi, Masao</au><au>Nakagawa, Susumu</au><au>Kasai, Tokuo</au><au>Kusuoka, Hideo</au><au>Takeishi, Yasuchika</au><au>Momose, Mitsuru</au><au>Takehana, Kazuya</au><au>Nanasato, Mamoru</au><au>Yoda, Syunichi</au><au>Nishina, Hidetaka</au><au>Matsumoto, Naoya</au><au>Nishimura, Tsunehiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study</atitle><jtitle>Journal of nuclear cardiology</jtitle><stitle>J. Nucl. Cardiol</stitle><addtitle>J Nucl Cardiol</addtitle><date>2019-04-01</date><risdate>2019</risdate><volume>26</volume><issue>2</issue><spage>431</spage><epage>440</epage><pages>431-440</pages><issn>1071-3581</issn><issn>1532-6551</issn><eissn>1532-6551</eissn><abstract>Myocardial perfusion imaging (MPI) is considered useful for risk stratification among patients with chronic kidney disease (CKD), without renal deterioration by contrast media.
The Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS 3) is a multicenter, prospective cohort study investigating the ability of MPI to predict cardiac events in 529 CKD patients without a definitive coronary artery disease. All patients were assessed by stress and rest MPI with 99mTc-tetrofosmin and data were analyzed using a defect scoring method and QGS software. Major cardiac events were analyzed for 3 years after registration. The mean eGFR was 29.0 ± 12.8 (mL/minute/1.73 m2). The mean summed stress/rest/difference (SSS, SRS, SDS) scores were 1.9 ± 3.8, 1.1 ± 3.0, and 0.8 ± 1.8, respectively. A total of 60 cardiac events (three cardiac deaths, six sudden deaths, five nonfatal myocardial infarctions, 46 hospitalization cases for heart failure) occurred. The event-free survival rate was lower among patients with kidney dysfunction, higher SSS, and higher CRP values. Multivariate Cox regression analysis independently associated SSS ≥8, eGFR <15 (mL/minute/1.73 m2), and CRP ≥0.3 (mg/dL) with cardiac events.
Together with eGFR and CRP, MPI can predict cardiac events in patients with CKD.</abstract><cop>Cham</cop><pub>Elsevier Inc</pub><pmid>28439760</pmid><doi>10.1007/s12350-017-0880-5</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1071-3581 |
| ispartof | Journal of nuclear cardiology, 2019-04, Vol.26 (2), p.431-440 |
| issn | 1071-3581 1532-6551 1532-6551 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6430747 |
| source | Springer Link |
| subjects | Adult Aged Aged, 80 and over C-reactive protein Cardiology Cardiovascular morbidity CONTRAST MEDIA CORONARIES DISEASE INCIDENCE Disease-Free Survival Electrocardiography estimated glomerular filtration rate Female Glomerular Filtration Rate HAZARDS HEART FAILURE Humans Imaging Japan Kidney Failure, Chronic - diagnostic imaging KIDNEYS Male Medicine Medicine & Public Health Middle Aged Multivariate Analysis MYOCARDIAL INFARCTION Myocardial Perfusion Imaging Nuclear Medicine Original Original Article PATIENTS Prognosis Proportional Hazards Models Prospective Studies Radiology RADIOLOGY AND NUCLEAR MEDICINE REGRESSION ANALYSIS Risk SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY Software TECHNETIUM 99 Tomography, Emission-Computed, Single-Photon Treatment Outcome |
| title | Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-03-09T13%3A40%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prognostic%20study%20of%20cardiac%20events%20in%20Japanese%20patients%20with%20chronic%20kidney%20disease%20using%20ECG-gated%20myocardial%20Perfusion%20imaging:%20Final%203-year%20report%20of%20the%20J-ACCESS%203%20study&rft.jtitle=Journal%20of%20nuclear%20cardiology&rft.au=Nakamura,%20Satoko&rft.date=2019-04-01&rft.volume=26&rft.issue=2&rft.spage=431&rft.epage=440&rft.pages=431-440&rft.issn=1071-3581&rft.eissn=1532-6551&rft_id=info:doi/10.1007/s12350-017-0880-5&rft_dat=%3Cproquest_pubme%3E1891896484%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c522t-463439cd07d31d87a00c02b982cef3a14849b7cbdeaa72cc3d25d3d4500cef443%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1891896484&rft_id=info:pmid/28439760&rfr_iscdi=true |