Genetic structure in the paternal lineages of South East Spain revealed by the analysis of 17 Y-STRs

The genetic data of 17 Y chromosome short tandem repeats in 146 unrelated donor residents in the provinces of Granada, Málaga, and Almería (GMA) were analyzed to determine the genetic legacy of the male inhabitants of the former Kingdom of Granada. A total of 139 unique haplotypes were identified. O...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2019-03, Vol.9 (1), p.5234, Article 5234
Main Authors: Saiz, María, Alvarez-Cubero, Maria Jesus, Lorente, José Antonio, Alvarez, Juan Carlos, Martinez-Gonzalez, Luis Javier
Format: Article
Language:English
Subjects:
45/22
45/23
45/77
631/181/457
631/208/457/649
Alleles
Chromosomes, Human, Y - genetics
Gene frequency
Genetic analysis
Genetic distance
Genetic Markers
Genetic structure
Haplotypes
Human Genetics
Humanities and Social Sciences
Humans
Male
Microsatellite Repeats
multidisciplinary
Population
Population genetics
Science
Science (multidisciplinary)
Short tandem repeats
Spain
Y chromosomes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The genetic data of 17 Y chromosome short tandem repeats in 146 unrelated donor residents in the provinces of Granada, Málaga, and Almería (GMA) were analyzed to determine the genetic legacy of the male inhabitants of the former Kingdom of Granada. A total of 139 unique haplotypes were identified. Observed allele frequencies and haplogroup frequencies were also analyzed. By AMOVA and STRUCTURE analysis, the populations of the 3 provinces could be treated genetically as a single population. The most frequent haplogroup was R1b1b2 (58.22%). By network analysis of all individuals, we observed a distribution according to haplogroup assignment. To improve the characterization of GMA population, it was compared with those of North Africa, the Iberian Peninsula, and southern Europe. In our analysis of allele frequencies and genetic distances, the GMA population lay within the Spanish population group. Further, in the STRUCTURE analysis, there was no African component in the GMA population, confirming that, based on our genetic markers, the GMA population does not reflect any male genetic influence of the North African people. The presence of African haplogroups in the GMA population is irrelevant when their frequency is compared with those in other European populations.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-41580-9