Magnetic Resonance Imaging (MRI) and Three-Dimensional Transvaginal Ultrasonography Scanning for Preoperative Assessment of High Risk in Women with Endometrial Cancer

BACKGROUND To evaluate the diagnostic performance of MRI and 3D-TVS for assessment of deep myometrial invasion (MI), cervical involvement (CI), and Lymph node metastases (LNM) in endometrial cancer staging before surgery. MATERIAL AND METHODS From January 2016 to December 2017, we reviewed data from...

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Bibliographic Details
Published in:Medical science monitor 2019-03, Vol.25, p.2024-2031
Main Authors: Yang, Ting, Tian, Sijuan, Li, Yang, Tian, Xueye, Wang, Wei, Zhao, Juan, Pei, Meili, Zhao, Minyi, Wang, Li, Quan, Shimin, Yang, Xiaofeng
Format: Article
Language:English
Subjects:
Adult
Aged
Cervix Uteri - diagnostic imaging
Cervix Uteri - pathology
Clinical Research
Endometrial Neoplasms - diagnostic imaging
Endosonography - methods
Female
Humans
Imaging, Three-Dimensional - methods
Lymphatic Metastasis - pathology
Magnetic Resonance Imaging - methods
Middle Aged
Myometrium - diagnostic imaging
Myometrium - pathology
Neoplasm Invasiveness - pathology
Preoperative Care - methods
Radionuclide Imaging
Sensitivity and Specificity
Ultrasonography - methods
Vagina - diagnostic imaging
Vaginal Neoplasms - diagnostic imaging
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Summary:BACKGROUND To evaluate the diagnostic performance of MRI and 3D-TVS for assessment of deep myometrial invasion (MI), cervical involvement (CI), and Lymph node metastases (LNM) in endometrial cancer staging before surgery. MATERIAL AND METHODS From January 2016 to December 2017, we reviewed data from 314 women with endometrial cancer who underwent preoperative MRI and 3D-TVS before surgery. The diagnostic sensitivity, specificity, PPV, NPV, and accuracy in detecting MI, CI, and LNM were estimated based on ultimate pathology results. RESULTS The sensitivity, specificity, PPV, NPV, and accuracy of MRI in the diagnosis of MI were 89.19%, 88.97%, 67.35%, 97.99%, and 89.01%, respectively, and the indexes of 3D-TVS for MI were 86.36%, 91.07%, 79.17%, 94.44%, and 89.74%, respectively. The sensitivity, specificity, PPV, NPV, and accuracy of MRI for CI were 75% and 92.35%, 40.9%, 98.13%, and 91.2%, respectively. The indicators of 3D-TVS were 77.78%, 94.29%, 63.63%, 97.06%, and 92.4%, respectively. There were no significant differences in sensitivity, specificity, NPV, and accuracy between MRI and 3D-TVS in the diagnosis of MI and CI. For MI and CI, the sensitivity of combined MRI and 3D-TVS was higher than any other single method (P
ISSN:1643-3750
1234-1010
1643-3750
DOI:10.12659/MSM.915276