Persistent metabolic acidosis on regular hemodialysis or peritoneal dialysis

Metabolic acidosis is known to have adverse consequences in patients with chronic kidney disease (CKD) including protein-energy wasting, inflammation, bone disease, and disturbance in endocrine function. Unlike in the management of patients with predialysis CKD, bicarbonate levels were not being rou...

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Bibliographic Details
Published in:Indian journal of nephrology 2019-03, Vol.29 (2), p.84-89
Main Authors: Goutham, K. T. C, Harichandrakumar, K, Dhanin, P, Priyamvada, P, Haridasan, S, Parameswaran, S
Format: Article
Language:English
Subjects:
Acidosis
Carbonates
Care and treatment
Chronic kidney failure
Comparative analysis
Complications and side effects
Energy management
Hemodialysis
Kidney diseases
Kidneys
Metabolism
Methods
Nephrology
Original
Patient monitoring equipment
Patient outcomes
Patients
Peritoneal dialysis
Risk factors
Urine
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Summary:Metabolic acidosis is known to have adverse consequences in patients with chronic kidney disease (CKD) including protein-energy wasting, inflammation, bone disease, and disturbance in endocrine function. Unlike in the management of patients with predialysis CKD, bicarbonate levels were not being routinely monitored in dialysis patients at our center. The KDOQI guidelines recommend serum bicarbonate levels ≥22 mEq/L in patients on dialysis. We measured the predialysis serum bicarbonate levels in 100 adult patients on regular hemodialysis (HD) and 41 adult patients on peritoneal dialysis (PD). We also studied the extent of rise in serum bicarbonate levels from predialysis levels after HD in our patients. Predialysis serum bicarbonate level was
ISSN:0971-4065
1998-3662
DOI:10.4103/ijn.IJN_309_17