Vaccine allergy

Five things to know about vaccine allergy are discussed. These are: 1. Immunoglobulin E-mediated vaccine allergies are uncommon, manifesting within minutes as urticaria, angioedema, wheeze or anaphylaxis. 2. The most common adverse events of vaccines are fever, local pain or irritation, and local re...

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Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2019-04, Vol.191 (14), p.E395-E395
Main Authors: Chu, Derek K., MD PhD, Abdurrahman, Zainab, MMath MD
Format: Article
Language:English
Subjects:
Allergens - adverse effects
Allergens - immunology
Allergies
Allergy
Anaphylaxis
Angioneurotic edema
Chicken pox
Complications and side effects
Drug Hypersensitivity - immunology
Drug Hypersensitivity - prevention & control
Egg Proteins - immunology
Hives (Disease)
Humans
Immunization
Immunoglobulin E
Immunoglobulin E - blood
Immunoglobulins
Influenza
Internal Medicine
Intradermal Tests
Measles
Practice
Practice Guidelines as Topic
Public health
Risk factors
Tropical diseases
Urticaria
Vaccination
Vaccines
Vaccines - adverse effects
Vaccines - immunology
Wheezing
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Summary:Five things to know about vaccine allergy are discussed. These are: 1. Immunoglobulin E-mediated vaccine allergies are uncommon, manifesting within minutes as urticaria, angioedema, wheeze or anaphylaxis. 2. The most common adverse events of vaccines are fever, local pain or irritation, and local redness or swelling, which are not signs of allergy. 3. Patients with egg allergy can be safely vaccinated with several vaccines without any special precautions. 4. Vaccine allergies are typically unpredictable and specific to a single vaccine. 5. Even if patients are truly allergic to a vaccine, allergists can often safely vaccinate them.
ISSN:0820-3946
1488-2329
DOI:10.1503/cmaj.190208