Ready-to-Use Supplemental Food for Nutritional Supplementation in Cystic Fibrosis

Undernutrition is common in cystic fibrosis (CF) and is correlated with long-term outcomes, yet current nutritional interventions have not demonstrated consistent improvements in energy intake, and subsequently, growth. Development of novel nutritional interventions to increase energy intake is esse...

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Bibliographic Details
Published in:Current developments in nutrition 2019-05, Vol.3 (5), p.nzz016-nzz016, Article nzz016
Main Authors: Pitman, Ryan T, Mui, Melody, Michelson, Peter H, Manary, Mark J
Format: Article
Language:English
Subjects:
Brief Communication: Research Report
children
cystic fibrosis
developing countries
dietary supplements
energy intake
linear programming
malnutrition
nutrient density
nutrition
nutritional intervention
nutritional supplement
ready-to-eat foods
ready-to-use supplemental food
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Summary:Undernutrition is common in cystic fibrosis (CF) and is correlated with long-term outcomes, yet current nutritional interventions have not demonstrated consistent improvements in energy intake, and subsequently, growth. Development of novel nutritional interventions to increase energy intake is essential to improve clinical outcomes of individuals with CF. Ready-to-use supplemental food (RUSF) is a modifiable, inexpensive, palatable, safe, and nutrient-dense food for treatment or prevention of acute malnutrition in developing countries. Utilizing a linear-programming tool we identified 6 RUSF formulations with sufficient nutrient density (495 kcal/100 g), protein, and fat for children with CF. Palatability was established by a taste-trial and affirmed by a 2-wk tolerability assessment that demonstrated consistent consumption and tolerance of the RUSF. Although preliminary, this study demonstrates the potential for developing RUSF as a nutritional supplement for increasing energy intake in children with CF.
ISSN:2475-2991
2475-2991
DOI:10.1093/cdn/nzz016