Whether Keratectasia Area Shown in Corneal Topography Is Appropriate for Evaluating the Effect of Corneal Cross-Linking for Keratoconus: A 12-Month Follow-Up Study

Purpose. To analyze the keratectasia area (KEA) shown in corneal topography before and after corneal cross-linking (CXL) in patients with progressive keratoconus (KC) and figure out whether KEA is appropriate for evaluating the effect of CXL. Methods. A retrospective analysis was conducted in 34 eye...

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Bibliographic Details
Published in:BioMed research international 2019-01, Vol.2019 (2019), p.1-5
Main Authors: Gao, Ning, Zhang, Huankai, Li, Zhiwei, Wang, Jia, Mu, Guo-ying
Format: Article
Language:English
Subjects:
Adolescent
Adult
Cataracts
Cell density
Child
Collagen
Contact lenses
Cornea
Cornea - physiopathology
Cornea - surgery
Cornea - ultrastructure
Corneal Topography - methods
Crosslinking
Endothelial cells
Epithelium, Corneal - growth & development
Epithelium, Corneal - pathology
Eye (anatomy)
Female
Follow-Up Studies
Humans
Keratectomy - methods
Keratoconus
Keratoconus - physiopathology
Keratoconus - surgery
Male
Patients
Pharmaceutical industry
Photochemotherapy
Physiology
Regression analysis
Regression models
Software
Statistical analysis
Surgery
Tomography
Topography
Visual Acuity
Vitamin B
Young Adult
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Summary:Purpose. To analyze the keratectasia area (KEA) shown in corneal topography before and after corneal cross-linking (CXL) in patients with progressive keratoconus (KC) and figure out whether KEA is appropriate for evaluating the effect of CXL. Methods. A retrospective analysis was conducted in 34 eyes from 24 progressive KC patients who have underwent CXL from 2015 to 2017. Area with K-value more than 47D shown in the corneal topography was marked and identified as KEA. Keratometry (K1, K2, and Kmax), KEA, thinnest corneal thickness (TCT), and endothelial cell density (ECD) were evaluated preoperatively or at months 3, 6, and 12 postoperatively. The changes of KEA before and after operation were evaluated. The relation of KEA and other parameters, including Kmax and TCT, was analyzed. Results. Linear regression model revealed the KEA, Kmax, K1, and K2 decreased after CXL in model y = 0.9622 -0.02408 x (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2019/1762537