Light Emitting Diode (LED) Phototherapy versus Conventional Phototherapy in Neonatal Hyperbilirubinemia: A Single Blinded Randomized Control Trial from Coastal India

Neonatal hyperbilirubinemia is a common problem with potentiality to cause irreversible brain damage. Reduction of serum bilirubin level is essential to minimize such damage. Compact fluorescent tubes, halogen bulbs, fiber optic blankets, and LEDs are commonly used light sources for phototherapy wit...

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Bibliographic Details
Published in:BioMed research international 2019-01, Vol.2019 (2019), p.1-6
Main Authors: Srinivasan, Mukund, Baliga, B. Shantharam, Mithra, Prasanna, Kamath, Sowmini P., Shenoy, Janardhan, Gutta, Sreesravya, Sarpangala, Muralikeshava
Format: Article
Language:English
Subjects:
Analysis
Babies
Bilirubin
Brain damage
Brain injury
Data collection
Excretion
Fiber optics
Fluorescence
Hyperbilirubinemia
Infants (Newborn)
Jaundice
Light emitting diodes
Light sources
Light therapy
Medical equipment
Neonatal jaundice
Neonates
Newborn babies
Optical fibers
Pediatrics
Phototherapy
Physiology
Random numbers
Randomization
Reduction
Side effects
Social sciences
Statistical tests
Tubes
Urine
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Summary:Neonatal hyperbilirubinemia is a common problem with potentiality to cause irreversible brain damage. Reduction of serum bilirubin level is essential to minimize such damage. Compact fluorescent tubes, halogen bulbs, fiber optic blankets, and LEDs are commonly used light sources for phototherapy with varying efficacies. This study aimed at evaluating the effect of LED versus conventional phototherapy on (a) rate of reduction in total serum bilirubin levels, (b) effect on urinary lumirubin excretion, and (c) comparing side effects of phototherapies among neonates with hyperbilirubinemia. In this randomized control trial, 166 neonates ≥ 35 weeks of age requiring phototherapy were recruited and further divided into 2 groups [LED (83) and conventional (83)] by using computer generated random numbers. Serial total serum bilirubin levels and random urinary lumirubin levels were collected and side effects of phototherapy were noted. Rate of fall in total serum bilirubin levels (TSB, μmol/L/hour) and random urinary lumirubin levels were computed. Data were collected using a pretested proforma. Analysis was done with Statistical Package for Social Sciences (SPSS) version 11.5. Independent sample “t” test and Chi-square tests were used with p value of
ISSN:2314-6133
2314-6141
DOI:10.1155/2019/6274719