Novel Approach to the Detection of Left Ventricular Hypertrophy Using Body Mass Index–Corrected Electrocardiographic Voltage Criteria in a Group of African Ancestry

Background Electrocardiographic (ECG) QRS voltages used to generate criteria for left ventricular hypertrophy (LVH) detection are considerably attenuated by obesity. This effect renders the utility of ECG criteria to detect LVH in obese individuals of African ancestry to be of limited value. Hypothe...

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Bibliographic Details
Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2016-09, Vol.39 (9), p.524-530
Main Authors: Robinson, Chanel, Woodiwiss, Angela J., Libhaber, Carlos D., Norton, Gavin R.
Format: Article
Language:English
Subjects:
Action Potentials
Adult
African Continental Ancestry Group
Area Under Curve
Body Mass Index
Clinical Investigations
Echocardiography
Electrocardiography
Electrocardiography - methods
Female
Genealogy
Heart Conduction System - physiopathology
Heart Rate
Humans
Hypertrophy, Left Ventricular - diagnosis
Hypertrophy, Left Ventricular - ethnology
Hypertrophy, Left Ventricular - physiopathology
Male
Middle Aged
Obesity - diagnosis
Obesity - ethnology
Obesity - physiopathology
Predictive Value of Tests
ROC Curve
South Africa - epidemiology
Ventricular Function, Left
Ventricular Remodeling
Young Adult
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Summary:Background Electrocardiographic (ECG) QRS voltages used to generate criteria for left ventricular hypertrophy (LVH) detection are considerably attenuated by obesity. This effect renders the utility of ECG criteria to detect LVH in obese individuals of African ancestry to be of limited value. Hypothesis A novel approach to correcting QRS voltages for the attenuating effect of body mass index (BMI) will improve the ability of ECG criteria to detect LVH in a group of African descent. Methods Left ventricular mass was determined from echocardiography in 661 randomly selected participants (43.0% obese) of black African ancestry in South Africa. Results As compared with Cornell and Sokolow‐Lyon voltage criteria, BMI best correlated with RaVL, Gubner‐Ungerleider, and Lewis QRS complex voltages, but these relations were noted only in those with BMI
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.22560