Feasibility and Acceptability of Real-Time Antiretroviral Adherence Monitoring among Depressed Women Living with HIV in the Deep South of the US

This study presents feasibility and acceptability data on the use of a real-time wireless electronic adherence monitor (EAM), among African American women living with HIV with co-occurring depression, residing in remote areas of the Southeastern United States. EAM and self-report ART adherence was m...

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Bibliographic Details
Published in:AIDS and behavior 2019-05, Vol.23 (5), p.1306-1314
Main Authors: Stringer, Kristi Lynn, Azuero, Andres, Ott, Corilyn, Psaros, Christina, Jagielski, Christina H., Safren, Steven A., Haberer, Jessica E., Kempf, Mirjam-Colette
Format: Article
Language:English
Subjects:
Acceptability
Acquired immune deficiency syndrome
Adhesion
Adult
African Americans
AIDS
Anti-Retroviral Agents - therapeutic use
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Behavior
Depression - epidemiology
Depression - psychology
Drug resistance
Feasibility Studies
Female
Health Psychology
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV Infections - psychology
Human immunodeficiency virus
Humans
Infectious Diseases
Intervention
Medication Adherence - psychology
Medication Adherence - statistics & numerical data
Medicine
Medicine & Public Health
Mental depression
Middle Aged
Monitoring
Monitoring, Physiologic - instrumentation
Original Paper
Patient Acceptance of Health Care
Patient compliance
Prescription drugs
Public Health
Real time
Rural areas
Southeastern United States - epidemiology
Time
Women
Womens health
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Summary:This study presents feasibility and acceptability data on the use of a real-time wireless electronic adherence monitor (EAM), among African American women living with HIV with co-occurring depression, residing in remote areas of the Southeastern United States. EAM and self-report ART adherence was monitored over an average of 14.8 weeks among 25 participants who were recruited at four HIV clinics in Alabama. Intra-class correlation showed a low degree of concordance between EAM and self-report (ICC = 0.33, 95% bootstrap CI 0.13, 0.59). 83% of data collected via EAM was transmitted in real-time. Due to technological failures, 11.4% were not transmitted in real-time, but were later recovered, and 5.7% were lost entirely. Acceptability was examined through surveys and qualitative interviews. Results suggest that EAM monitoring is acceptable and feasible in a rural US setting; however, technological difficulties, such as loss of connectivity may impede the device’s usefulness for just-in-time adherence interventions.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-018-2322-z