Loading…

Chinese Guidelines for the Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack 2010

The risks of recurrent stroke are different, because the causes and the pathophysiological mechanisms of ischemic stroke/transient ischemic attack (TIA), the locations of vascular diseases, risk factors, and patients’ compliance are so variable. Studies in China suggest a logistic relationship betwe...

Full description

Saved in:
Bibliographic Details
Published in:CNS neuroscience & therapeutics 2012-02, Vol.18 (2), p.93-101
Main Authors: Wang, Yong-Jun, Zhang, Su-Ming, Zhang, Liqun, Wang, Chun-Xue
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The risks of recurrent stroke are different, because the causes and the pathophysiological mechanisms of ischemic stroke/transient ischemic attack (TIA), the locations of vascular diseases, risk factors, and patients’ compliance are so variable. Studies in China suggest a logistic relationship between elevated blood pressure (BP) and the risk of stroke [ 2]: for every 10 mmHg elevation of systolic BP from baseline, the relative risk of stroke increases 49%; for every 5 mmHg elevation of diastolic BP, the relative risk of stroke increases 46%. 2 For patients with stroke/TIA and multiple risk factors (such as coronary artery disease, diabetes, current smoking, metabolic syndrome, cerebrovascular atherosclerosis without evidence of unstable plaque, arterial thrombosis or peripheral arterial disease), it is reasonable to target a LDL‐C level of 40% in LDL‐C (Class I, Level of Evidence A). 3 Patients with ischemic stroke/TIA and evidence of intra‐ and extracranial large artery atherosclerosis and unstable plaques or arterial thrombosis, are recommended early intensive statin therapy to target a LDL‐C level of 40% in LDL‐C (Class III, Level of Evidence C).
ISSN:1755-5930
1755-5949
1755-5949
DOI:10.1111/j.1755-5949.2011.00290.x