Lipometabolism and Glycometabolism in Liver Diseases

The liver is the main metabolic organ in the body especially in lipometabolism and glycometabolism. Carbohydrates and fats disorders can result in insulin resistance in the liver. Metabolic imbalance can even lead to life-threatening conditions. Therefore, it is essential to maintain the normal meta...

Full description

Saved in:
Bibliographic Details
Published in:BioMed research international 2018-01, Vol.2018 (2018), p.1-7
Main Authors: Shi, Xiao-lei, Ren, Hao-zhen, Wang, Jing-lin, Ding, Hao-ran
Format: Article
Language:English
Subjects:
Carbohydrates
Diabetes
Diseases
Disorders
Fats
Fatty acids
Glucose
Hepatology
Homeostasis
Insulin
Insulin resistance
Insulin-like growth factors
Kinases
Lipids
Liver
Liver cancer
Liver diseases
Metabolic disorders
Metabolism
Metabolites
Oxidative stress
Physiological aspects
Review
Triglycerides
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The liver is the main metabolic organ in the body especially in lipometabolism and glycometabolism. Carbohydrates and fats disorders can result in insulin resistance in the liver. Metabolic imbalance can even lead to life-threatening conditions. Therefore, it is essential to maintain the normal metabolic function of the liver. When the liver is in a pathological state, liver metabolism homeostasis is damaged, and metabolic disorders will further aggravate liver disease. Consequently, it is essential to determine the relationship between liver diseases and metabolic disorders. Here we review a lot of evidence that liver diseases are closely related to lipometabolism and glycometabolism. Although the disorder of the liver metabolism is caused by different liver diseases, the break of metabolic balance is determined by changes in the state of the liver. We discuss the relationship between liver disease and metabolic changes, outline the process of how metabolic changes are regulated by liver diseases, and describe the role which metabolic changes play in the process and prognosis of liver disease.
ISSN:2314-6133
2314-6141
DOI:10.1155/2018/1287127